View Solution Identify the components labelled A, B, C and D in the diagram below from the list (i) to (viii) given along with Components : (i) Cristae of mitochondria (ii) Inner membrane of mitochondria (iii) Cytoplasm (iv) Smooth endoplasmic reticulum ...
Here we report endoplasmic reticulum-associated degradation (ERAD) as a protein quality checkpoint that controls the haematopoietic stem cell (HSC)–niche interaction and determines the fate of HSCs. The SEL1L–HRD1 complex, the most conserved branch of ERAD4, is highly expressed in HSCs. ...
The defects in storage proteins secretion in the endosperm of transgenic rice seeds often leads to endoplasmic reticulum (ER) stress, which produces floury and shrunken seeds, but the mechanism of this response remains unclear. We used an iTRAQ-based proteomics analysis of ER-stressed rice seeds ...
The endoplasmic reticulum (ER) is an intracellular organelle that responsible for the three-dimensional folding of newly synthesized proteins. When there is an overload of unfolded or misfolded protein accumulated in the ER lumen, a set of proteins on the ER are activated to re-establish homoeost...
PsAvh262 and GmBiP1 co-localize in the endoplasmic reticulum. To gain insights into the functional significance of the PsAvh262- GmBiP1 interaction, we determined the localization patterns of the proteins in plant cells. Wild-type or mutant PsAvh262 proteins (lacking the signal peptide) ...
For the first time, we provide strong evidence that Hsp60 is localized in the endoplasmic reticulum (ER) during breast cancer cell apoptosis. In addition, adapting mass fingerprinting approach, we have also identified that anti-tumor activity of this particular fraction against breast cancer cells ...
23 September 2015 Proteomic analysis of endoplasmic reticulum stress responses in rice seeds Dandan Qian, Lihong Tian & Leqing Qu The defects in storage proteins secretion in the endosperm of transgenic rice seeds often leads to endoplasmic reticulum (ER) stress, which produces floury and shr...
mitochondrial voltage-dependent anion channel 1 (VDAC1), tyrosine phosphatase-interacting protein 51 (PTPIP51), vesicle-associated protein (VAPB), sigma 1 receptors (S1R), enzymes involved in ER redox regulation (e.g., endoplasmic reticulum oxidoreductin 1-α (Ero1-α)), and certain chaperone...
endoplasmic reticulum (ER); morphology; dynamics; anomalous diffusion; membrane contact site (MCS); dynein; kinesin; microtubule 1. Introduction The endoplasmic reticulum (ER) is a subcellular organelle responsible for a variety of essential cellular functions. In the ER, proteins are synthesised and...
International Journal of Molecular Sciences Review Toxins Utilize the Endoplasmic Reticulum-Associated Protein Degradation Pathway in Their Intoxication Process Jowita Nowakowska-Gołacka, Hanna Sominka, Natalia Sowa-Rogozin´ ska and Monika Słomin´ ska-Wojewódzka * Department of Medical Biology ...