in which R1, R2, R3, R4 and A have the meaning given in the description.PETERSEN, UWE, DR., LEVERKUSEN, DESCHENKE, THOMAS, DR., BERGISCH GLADBACH, DESCHRIEWER, MICHAEL, DR., ODENTHAL, DEKREBS, ANDREAS, DR., ODENTHAL, DEGROHE, KLAUS, DR., ODENTHAL, DEHALLER, INGO, DR., WUPPERTAL...
(−)3-((S)-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)(3-thienyl)methyl)phenol and pharmaceutically acceptable esters or salts thereof, in essentially enantiomerically pure form hav
1.A process for preparing an enantiomerically pure (stereomerically pure) compound of formulain whichR1 is 2-7C-alkyl substituted by —N(R111)R112,R111 is 1-4C-alkyl, 2-4C-alkenyl, 2-4C-alkinyl, 3-7C-cycloalkyl, 3-7C-cycloalkyl-1-4C-alkyl, hydroxy-2-4C-alkyl, 1-4C-alkoxy-2-...
Synthesis of enantiomerically pure non proteinogenic β-amino acids Proline-catalyzed diastereoselective aminomethylation of aldehydes using a chiral iminium ion, generated from a readily prepared precursor, provides alpha-... L Lecointe,J Receveur,V Rolland,... 被引量: 0发表: 1999年 ...
A ketone of formula (II) wherein R<1> has the aforementioned meaning is asymmetrically hydrogenated.GEWALD, RAINER
Intermediates for the synthesis of enantiomerically pure alpha-lipoic acid; said hydrogenation includes presence of ruthenium-phosphine complexdoi:US6229042 B1in which R 1 and R 2 have the above meaning, is asymmetrically hydrogenated.Rainer Gewald...
The present invention relates to compounds of formula (I) which include racemic mixtures of (+) - 1 and enantiomerically pure compounds of (-) - 1 and (+) - in formula (1) R2 and R3 have the same or different meaning. hydrogen, chlorine or fluorine, or methyl, trifluoromethyl or ...
The invention relates to enantiomerically pure 2-azetidinones, of the general formula (I) in which R<1>, R<2> and R<3> have the meaning indicated in the description, to processes for their preparation and to their use as intermediates for the synthesis of carbapenem antibiotics.doi:DE3...
Process for the preparation of enantiomerically pure 3-hydroxyoctanedioic acid diesters by asymmetric catalytic hydrogenation[P].US 6013833 2000.Rainer G,Gunter L.Process for the preparation of enantiomerically pure 3-hydroxyoctanedioic acid diesters by asymmetric catalytic hydrogenation:US,6 013 833[P]...
The invention relates to a new process for the preparation of optically active amino acids and amino acid derivatives of the general formula (I), wherein *, X and R 1 to R 4 have the meaning given in the description. Starting from commercially obtainable (-)-menthol or (+)-menthol, ...