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this signaling pathway has been implicated in multiple processes during regeneration, including cardiomyocyte cell cycle progression and EMT. In this study, the involvement of a CM EMT-like response
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The molecular signaling pathways of EMT Intensive study over the past 2 decades has revealed many upstream regulators and oncogenic signaling pathways regulating EMT-TFs (Fig.3). While many of these constitute EMT regulatory pathways [e.g. Wnt, Notch, Hedgehog (HH), Transforming growth factor bet...
Dyrskjot L, Zieger K, Real FX, Malats N, Carrato A, Hurst C, Kotwal S, Knowles M, Malmstrom PU, de la Torre M, et al: Gene expression signatures predict outcome in non-muscle-invasive bladder carcinoma: a multicenter validation study. Clin Cancer Res. 2007, 13 (12): 3545-3551....
The experiments and procedures described in this study were carried out in accordance with the Guide for the Care and Use of Laboratory Animals as adopted and promulgated by the National Institutes of Health, and were approved by the Animal Care Committee of Kumamoto University. Cell culture and ...
Study approval All animal procedures were approved by the Center for Animal at Jinan University in accordance with the NIH Guide for the Care and Use of Laboratory Animals (National Academies Press 2011) and the Animal Welfare Act. The immunohistochemistry study used breast carcinoma tissues was ...
TRPS1 was positively associated with ER and PR expressions and negatively as- sociated with HER2 status, which is consistent with previ- ous study [6]. When the cut-off level score for TRPS1 to be positive is 1, the TRPS1 was not remarkably associated with the tumour grade, pathological...
In the present study, the specific mechanisms by which FAM83A and FAM83A-AS1 cofunction in the Wnt/β-catenin and EGFR signaling pathways were reviewed in detail, which will guide subsequent research. We also described the applications of FAM83A and FAM83A-AS1 in tumor therapy and provided...