CANCER invasivenessPHENOMENOLOGICAL biologyEMBRYOLOGYEpithelial-to-mesenchymal transition (EMT), a biological phenomenon of cellular plasticity initially reported in embryonic development, has been increasingly recognized for its importance in cancer progression and metastasis. Despite tremendous progress ...
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早!今天和大家分享一篇单细胞癌症模型的肿瘤分析文,发表在Cancer Research杂志(IF:12.7),题目是Cellular Model of Colon Cancer Progression Reveals Signatures of mRNAs, miRNA, lncRNAs, and Epigenetic Modifications Associated with Metastasis。 摘要 转移占癌症死亡...
Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy. Oncogene. 2017;36(5):667-77.Gugnoni M, Sancisi V, Gandolfi G, et al. Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy. Oncogene. 2017;36(5): 667-677....
1. Role of autophagy in cancer metastasis In order to degrade long-standing cellular proteins and organelles, autophagy is triggered, which is not only important in normal development and response to changing environmental stimuli but also a chief component in diseases like cancer [5]. At the bas...
The molecular mechanisms underlying cancer progression and metastasis are still poorly understood. In recent years, the epithelial-to-mesenchymal transition (EMT), a traditional phenomenon revealed in embryonic development, has been gradually accepted as a potential mechanism underlying cancer progression and...
Cancer metastasis, which is the dissemination of tumor cells into distant organs, is the leading cause of mortality in cancer patients. To undergo metastasis, cells must leave the primary tumor, circulate into the blood, colonize distant organs, and form distant metastasis. It has been proposed ...
et al. Epithelial-to-Mesenchymal Transition Signaling Pathways Responsible for Breast Cancer Metastasis...