in mouse embryonic stem cells (ESC) and neuronal stem cells (NSC). Biotin labeling of H3.3-SNAP was performed at 0 h and followed over subsequent 3, 6, and 12 h9. Each datapoint is calculated as the log2 value of the mean coverage in each sample bin divided by the mean...
Preparation and characterization of embryonic stem cell (ESC)-derived extracellular vesicle-mimetic nanovesicles (ESC-NVs). ( Schematic diagram of the experimental procedure for preparation of ESC-NVs. Representative transmission electron micrograph images of ESC and ESC-NVs. Scale bars=1000nm (ESC) ...
Functional annotation analysis of the transcriptome of differentiating embryonic stem cells exposed downregulated components of DNA replication, recombination and repair machinery, cell cycling, cancer mechanisms, and RNA post-translational modifications. Concomitantly, cardiovascular development, cell-to-cell sign...
Cardiomyocytes derived from pluripotent stem cells (PSC-CMs) have been widely accepted as a promising cell source for cardiac drug screening and heart regeneration therapies. However, unlike adult cardiomyocytes, the underdeveloped structure, the immatur
The structures of the three SPC promoter–Neor transgene vectors used to generate hES-ATIIC lines are schematically diagramed. Each diagram is drawn to depict relevant information, so they are not to exact scale. The details regarding construction of the transgene vectors are described in Materials...
C, diagram of 1-bp deletion in Crygc and the sequence of sgRNA targeting Crygc. D, filtered haploid cells carrying the 35-kb deletion in Iqgap2 supported the birth of SC mice. E, genetic trait analysis revealed that the SC mice generated in D all carried the heterozygous mutation in Iq...
Cardiomyocytes derived from pluripotent stem cells (PSC-CMs) have been widely accepted as a promising cell source for cardiac drug screening and heart regeneration therapies. However, unlike adult cardiomyocytes, the underdeveloped structure, the immatur
Dictionary of Unfamiliar Words by Diagram Group Copyright © 2008 by Diagram Visual Information Limited Translations Spanish / Español Select a language: quiste cyst [sɪst]N→quistem Collins Spanish Dictionary - Complete and Unabridged 8th Edition 2005 © William Collins Sons & Co. Ltd. 19...
Embryonic stem (ES) cells are pluripotent, not genetically modified cells isolated from preimplantation embryos. The establishment of human ES cells enables the production of large numbers of human cell types to evaluate the effects of chemicals on disease and toxic response. This review provides an...
Cardiomyocyte transplantation after heart attack improves contractile function in monkeys. Pluripotent stem cell–derived cardiomyocyte grafts can remuscularize substantial amounts of infarcted myocardium and beat in synchrony with the heart, but in some