Elevated beta thromboglobulin in peripheral venous blood of patients with acute myocardial ischemia: direct evidence for enhanced platelet reactivity in vivo. Am J Cardiol. 1981;48: 395-402.Smitherman TC, Milam M, Woo J, et al. Elevated beta thromboglobulin in peripheral venous blood of ...
We assessed if elevated protein synthesis in neurons leads to abnormal behaviors in mice. As revealed in rotarod and open-field tests (Supplementary Fig.2b, c), NN4Emice had intact motor function. We examined anxiety-like behaviors by performing open field, elevated plus maze, and light-dark ...
The majority of paraproteins migrate to the gamma globulin region, although occasionally, immunoglobulin A monoclonal proteins will migrate to the beta zones. Elevated gamma globulins may be polyclonal in situations such as chronic inflammation or infection. When a monoclonal protein is present at a ...
Estrogen receptors alpha and beta (ERα and ERβ), together with the membrane associated G-protein-coupled functional ER (GPER), and the enzyme cytochrome P450 aromatase, which converts testosterone to estrogen, are abundant within the testis2,3,4. Estradiol is produced in immature germ cells,...
Culina S et al (2018) Islet-reactive CD8(+) T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors. Sci Immunol. https://doi.org/10.1126/sciimmunol.aao4013 Article PubMed PubMed Central Google Scholar Gonzalez-Duque S et al (2018...
with plasma levels peaking at night because synthesis is inhibited by light exposure [2,3]. To elicit its circadian functions, melatonin binds to G protein-coupled receptors (GPCRs) such as the melatonin receptor type 2 (MT2) on pancreatic beta cells [4,5,6], whereby rising circulating mel...
Elevated Erythropoietin mRNA and Protein Concentrations in the Developing Human Eye SHRENA PATEL, MICHAEL J. ROWE, SALLY A. WINTERS, AND ROBIN K. OHLS Department of Pediatrics [S.P.], University of Utah, Salt Lake City, UT 84132; Department of Pediatrics [M.J.R., S.A.W., R.K.O.]...
Here we show, using proteomics profiling to screen plasma from patients with suspected acute VTE, and several case-control studies for VTE, how Complement Factor H Related 5 protein (CFHR5), a regulator of the alternative pathway of complement activation, is a VTE-associated plasma biomarker. ...
AHSP is part of the heat-shock protein family, proteins that are produced in response to stressors, such as heat, oxidizing conditions, and toxins. Such adaptive responses may take weeks before being manifested (Ferns et al 2006; Wang et al 2005; Papp et al 2003). Reduced AHSP can mean...
hypertension- a common disorder in which blood pressure remains abnormally high (a reading of 140/90 mm Hg or greater) high blood pressure cardiovascular disease- a disease of the heart or blood vessels essential hypertension,hyperpiesia,hyperpiesis- persistent and pathological high blood pressure fo...