The book presents a comprehensive introduction to the study of topological transformation groups and provides a systematic exposition of the fundamental methods and techniques oftopological dynamics sufficient for understanding recent research papers in this field. The emphasis is on the clarity of the ...
Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation. Cell 148, 84–98 (2012). CAS PubMed PubMed Central Google Scholar Sanyal, A., Lajoie, B. R., Jain, G. & Dekker, J. The long-range interaction landscape of gene promoters. Nature ...
where 1,176 genes had one reference and one alternative promoter and 117 genes had two or more alternative promoters. Correlation of expression levels of reference and alternative promoter pairs indicated both convergent (cyan in Fig.3a,b) and divergent (brown) dynamics during development. The expr...
During the last few years several good textbooks on nonlinear dynamics have ap peared for graduate students in applied mathematics. It seems, however, that the majority of such books are still too theoretically oriented and leave many practi cal issues unclear for people intending to apply...
Multi-objective topological design considering functionally graded materials and coated fiber reinforcement Hyunseung Ryu, Jeonghoon Yoo Article 104269 Article preview select article Adaptive stopping criterion of iterative solvers for efficient computational cost reduction: Application to Navier–Stokes with ther...
calculating stereo descriptors cns mpo score predictor bbb score predictor herg predictor molecular modeling plugins charge plugin orbital electronegativity plugin polarizability plugin dipole moment calculation plugin conformer plugin 3d alignment plugin molecular dynamics plugin structural property plugins elemental...
For completeness, relevant up-to-date software tools, used at various stages of RVE generation – either commercial or open-source – are summarized. Considered methods are reviewed based on their efficiency and predictive performance with respect to geometrical and topological properties of the ...
(MD) simulations with HPC capabilities in Azure Quantum Elements. Such workloads play an important role in life sciences by simulating the structure and dynamics of proteins, the ligands bound to them, and their associated affinities. This structural exploration can accelerate the inno...
The organization of chromatin in the nucleus plays an essential role in gene regulation. About half of the mammalian genome comprises transposable elements. Given their repetitive nature, reads associated with these elements are generally discarded or ra
The resulting gels were exposed to phosphorimage screens (Molecular Dynamics) and analyzed by using a Typhoon phosphorimager. ImageQuant software (GE Healthcare) was used to measure observed band intensities to derive the population of each fragment size at a given timepoint. These data were used ...