Younger patients or African-American women are most vulnerable to TNBC.1 TNBC lacks estrogen receptor (ER) and progesterone receptor (PR) overexpression and human epidermal growth factor receptor 2 (HER2) amplification.2–4 TNBC is typically associated with a large size, higher g...
The aim of this study, grounded in Asset Based Community developing plus the Model of youngsters’ Health and its Influences, would be to identify and comprehend these aspects through the lens of parents residing predominantly African-American low-income communities within Washington, DC. An ...
Your test result typically includes a reference range for what the laboratory considers normal eGFR levels. For eGFR based on creatinine levels, many laboratories list separate reference ranges for African Americans and non-African Americans because some prior studies have found varying eGFR levels among...
The only African study in literature is from Morocco and didn’t report concurrent mutations [24]. ADC histology and smoking history are the only significant independent predictors of EGFR mutation status [29]. Concurrent mutations were found in 43.7% of mutated men, all smokers exceeding 40 ...
Among whites we used 1000 Genomes precomputed LD Scores and for non-Hispanic blacks we calculated LD Scores in 2217 African American participants from BioVU using Illumina Mega Array (Illumina, Inc) genotype data imputed to 1000 Genomes phase 3 haplotypes. Calculation of the intercept in the MVP...
Morris GJ, Naidu S, Topham AK, Guiles F, Xu Y, McCue P, Schwartz GF, Park PK, Rosenberg AL, Brill K, Mitchell EP: Differences in breast carcinoma characteristics in newly diagnosed African-American and Caucasian patients. Cancer. 2007, 110: 876-884. 10.1002/cncr.22836. PubMed Google ...
NSCLC is 51% in the pediatric population, with a survival rate of only 26% [7]. However, the occurrence of pediatric lung cancer is 0.049 per 100,000 population [8]. Also, the mortality rate of NSCLC is double in the African-American male as opposed to Asian-Americans, which accounts ...
The study of African American (AA) and European American women found 59 differently expressed genes, while another study found differences of multiple positive and negative genes between black and white women [15,16]. To our knowledge, no such studies were performed with CMTs, except an ...
Median age at diagnosis was 63.9 years, with an interquartile range of 56.7 to 71.9 years. Our patient population was predominantly female (102/137 patients, 74.4%), and 45.2% were never smokers. Patient race was 62.8% white, 21.9% black or African American, and 8.8% Asian. A total of...
The original source of the cell lines is the American Type Culture Collection (ATCC, Manassas, VA, USA). The cells were cultivated in a completed DMEM culture medium with GlutaMAX (Invitrogen, Germany) supplemented with 10% fetal bovine serum, l-glutamine (2 mM), and 1% of a 10,000 U...