African-Americans with COX-2-positive tumors had a statistically non-significant higher risk of death than African-Americans with COX-2-negative tumors (HR 5.58, 95% CI 0.64–48.37). No association between COX-2 expression and survival was observed among Caucasians (HR 1.29, 95% CI 0.72–...
Your test result typically includes a reference range for what the laboratory considers normal eGFR levels. For eGFR based on creatinine levels, many laboratories list separate reference ranges for African Americans and non-African Americans because some prior studies have found varying eGFR levels among...
Morris GJ, Naidu S, Topham AK, Guiles F, Xu Y, McCue P, Schwartz GF, Park PK, Rosenberg AL, Brill K, Mitchell EP: Differences in breast carcinoma characteristics in newly diagnosed African-American and Caucasian patients. Cancer. 2007, 110: 876-884. 10.1002/cncr.22836. PubMed Google ...
Among whites we used 1000 Genomes precomputed LD Scores and for non-Hispanic blacks we calculated LD Scores in 2217 African American participants from BioVU using Illumina Mega Array (Illumina, Inc) genotype data imputed to 1000 Genomes phase 3 haplotypes. Calculation of the intercept in the MVP...
Morris GJ, Naidu S, Topham AK, Guiles F, Xu Y, McCue P, Schwartz GF, Park PK, Rosenberg AL, Brill K, Mitchell EP: Differences in breast carcinoma characteristics in newly diagnosed African-American and Caucasian patients. Cancer. 2007, 110: 876-884. 10.1002/cncr.22836. PubMed Google ...
Viruses, cell lines, and compounds The PRRSV of genotype 2 (GD-ZJ, GenBank: MF772778.1, American type) and MARC-145 cells were generously provided by Professor Song’s lab [15]. MARC-145 is a cell line that is permissive to PRRSV, cultured in Dulbecco’s Minimum Essential Medium (DMEM...
Black or African American 1 (1.9) 1 (1.9) 1 (1.8) American Indian or Alaskan Native 1 (1.9) 0 0 White 46 (88.5) 48 (92.3) 54 (94.7) Unknown 3 (5.8) 1 (1.9) 1 (1.8) ECOG PS, n (%) 0 16 (30.8) 22 (42.3) 22 (39.3) 1 36 (69.2) 30 (57.7) 34 (60.7) Positive E...
Molecular testing for selection of patients with lung cancer for epidermal growth factor receptor and anaplastic lymphoma kinase tyrosine kinase inhibitors: American Society of Clinical Oncology endorsement of the College of American Pathologists/international association for the study of lung cancer/...
A 53-year-old, North-African male, never-smoker, with a performance status of (PS) 1, was diagnosed by tissue biopsy with T4N2M1a lung adenocarcinoma (LAC) (Figure 1a) harboring EGFR ex19del (p.E746_A750del). This variant was also detected in baseline plasma cfDNA, with a variant al...
Cell Line cells were obtained from American Type Culture Collection. Cells were cultured using DMEM (Invitrogen/Life Technologies, Carlsbad, CA, USA) supplemented with 10% FBS (Hyclone, Logan, UT, USA), 10 μg/mL of insulin (Sigma, St. Louis, MI, USA), and 1% penicillin-streptomycin. ...