Younger patients or African-American women are most vulnerable to TNBC.1 TNBC lacks estrogen receptor (ER) and progesterone receptor (PR) overexpression and human epidermal growth factor receptor 2 (HER2) amplification.2–4 TNBC is typically associated with a large size, higher g...
However, African-American males have a two-times higher prevalence of oral and pharynex cancer incident rate and lower five-year survival rate in comparison to Caucasians males. The disparity in oral health and oral health outcomes is the result of environmental and genetic influences. Epidermal ...
Your test result typically includes a reference range for what the laboratory considers normal eGFR levels. For eGFR based on creatinine levels, many laboratories list separate reference ranges for African Americans and non-African Americans because some prior studies have found varying eGFR levels among...
According to research, certain ethnicities are more susceptible to EGFR mutations. People of Asian descent who developnon-small cell lung cancer (NSCLC)are almost 47% more likely to have the mutation. Among those of Middle-Eastern or African descent, the estimate is approximately 21%, while thos...
African American 17 (10) 1.28 (0.29–5.19) Other 5 (2.9) Unknown 5 (2.9) Smoking status 0.5292 0.516 Current/former 158 (92.9) 2.291 (0.209–12.188) 252 (75.2) 1.703 (0.152–9.781) Never 9 (5.3) 2.807 (0.513–13.58) 28 (8.3) 1.391 (0.276–6.849) Unknown 3 55 NA, not ...
The aim of this study, grounded in Asset Based Community developing plus the Model of youngsters’ Health and its Influences, would be to identify and comprehend these aspects through the lens of parents residing predominantly African-American low-income communities within Washington, DC. An ...
This may be a Tunisian specificity, perhaps in relation with high frequency of smokers, noting that most studies enrolled Asian patients [20]. The only African study in literature is from Morocco and didn’t report concurrent mutations [24]. ADC histology and smoking history are the only ...
Among whites we used 1000 Genomes precomputed LD Scores and for non-Hispanic blacks we calculated LD Scores in 2217 African American participants from BioVU using Illumina Mega Array (Illumina, Inc) genotype data imputed to 1000 Genomes phase 3 haplotypes. Calculation of the intercept in the MVP...
Morris GJ, Naidu S, Topham AK, Guiles F, Xu Y, McCue P, Schwartz GF, Park PK, Rosenberg AL, Brill K, Mitchell EP: Differences in breast carcinoma characteristics in newly diagnosed African-American and Caucasian patients. Cancer. 2007, 110: 876-884. 10.1002/cncr.22836. PubMed Google ...
We also examined the impact of concurrent genomic alterations on clinical outcomes in patients with wildtype EGFR or non-active EGFR mutations. In this analysis, patients with STK11 mutation were found to have significantly shorter DFS (p = 0.006, Table 5) and OS (p = 0.046, see ...