Subsequently, seven-day continual infusion of C225 or AG1478 in rats: reduced the expression of phospho-EGFR, phosphorylation of Erk and p38 MAPK, and production of IL-1尾 and TNF伪; lessened neuroinflammation-associated secondary damage, like microglia/astrocyte activation, tissue edema and glial ...
Here we report that copper stimulates the endocytosis of PrP-sen via a caveolin-dependent pathway in both microglia and neuroblastoma cells. We show that ... Marella,M. - 《Journal of Biological Chemistry》 被引量: 247发表: 2002年 Epidermal Growth Factor-stimulated Tyrosine Phosphorylation of Cav...
The consumption of nuts does not result in a higher body weight; possible energy regulatory mechanisms include a decrease in subsequent energy intake and an increase in energy expenditure. This research aimed to explore how tree nut and peanut consumption affected energy intake, compensation, and exp...
13. 慢性活动性多发性硬化症中的淋巴细胞-小胶质细胞-星形胶质细胞轴 A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis 多发性硬化症(MS),其不会在几个月后解决它们形成怀有持续脱髓鞘和轴突变性,并在体内识别通过核磁共振扫描他们的顺缘病变。在这里,定义这种致残性、渐进性神经退行性...
et al. TET2 regulates the neuroinflammatory response in microglia. Cell Rep. 29, 697–713.e698 (2019). Article CAS PubMed Google Scholar Xu, Y. P. et al. Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacy. J. Clin. Investig. 129, 4316–4331 (2019). Article Pub...
A forward loop between glioma and microglia: glioma-derived extracellular matrix-activated microglia secrete IL-18 to enhance the migration of glioma cells. J Cell Physiol 2012; 227: 558–568. Article CAS PubMed Google Scholar Markovic DS, Vinnakota K, Chirasani S, Synowitz M, Raguet H, ...
Microglia in the central nervous system (CNS) play an important role in the initiation of neuroinflammatory response. Icariin, a compound from Epimedium br... KW Zeng,F Hong,GX Liu,... - 《International Immunopharmacology》 被引量: 153发表: 2010年 TAK1-mediated stress signaling pathways are ...
A forward loop between glioma and microglia: glioma-derived extracellular matrix-activated microglia secrete IL-18 to enhance the migration of glioma cells. J Cell Physiol 2012; 227: 558–568. Article CAS PubMed Google Scholar Markovic DS, Vinnakota K, Chirasani S, Synowitz M, Raguet H, ...
The p53 transcription factor modulates microglia behavior through microRNA-dependent regulation of c-Maf. Journal of immunology 192, 358–366, doi: 10.4049/jimmunol.1301397 (2014). 33. Suzuki, H. I. & Miyazono, K. p53 actions on microRNA expression and maturation pathway. Methods in molecular...
It is interesting to note that microglia express receptors for binding of the Fc part of antibodies and might there- fore react with nimotuzumab-bound GB cells similar to mechanistic hypotheses of antibody mediated plaque clearance in Alzheimer's models [26]. Further clarifying potential antibody ...