ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CBC, complete blood count; eGFR, estimated glomerular filtration rate; HAV, hepatitis A virus; hCG, human chorionic gonadotropin; HCV, hepatitis C virus; HDL, high-density lipoprotein; HIV,...
Clinical utility of a blood-based EGFR mutation test in patients receiving first-line erlotinib therapy in the ENSURE, FASTACT-2, and ASPIRATION studiesArticleObjective: Patients with advanced non-small-cell lung cancer (NSCLC) with an adenocarcinoma component are recommended to undergo epidermal ...
河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师(或指导小组)的指导下,由本人独立完成。本学位论文研究所获得的研究成果,其知识产权归河北医科大..
Blood or plasma stability of test compounds (1a, 2a, 4d, and 4c) were evaluated by calculating the remaining percentage in in vitro incubation system, in which 5 μM of each test compound was incubated with blood or plasma at 37 °C for 60 min. Incubated samples were analyzed by...
The European Organisation for Research and Treatment of Cancer has indicated that the main predictors of a negative prognosis are a poor performance status (PS), high white blood cell counts, male gender, a sarcomatoid subtype, anaemia, *Correspondence: Professor R Boldorini; E-mail: renzo.bold...
4、A Mini KitDxS EGFR Mutation Test Kit (DxS,Manchester, UK)48.2%95.4%90.0%68.1%73.5%Jie Wang2744YesPlasmaQIAamp DNA Mini KitDHPLC68.4%83.4%70.0%82.3%80.0%Britta Weber3196NoPlasmacobas DNA Sample Preperation KitARMS cobas EGFR Blood Test60.7%96.4%73.9%93.5%91.3%NCT012039174652YesPlasmaQIAamp ...
Möglicherweise ist der verwendete Test hier nicht spezi sch genug. Friederike Klein Mayo-de-las-Casas C et al. Large scale, prospecti- ve screening of EGFR mutations in the blood of advanced NSCLC patients to guide treatment de- cisions. Ann Oncol. 2017;28(9):2248-55. kurz notiert ...
normal control PBMC: peripheral blood mononuclear cells PI3K: phosphatidylinositol 3-kinase PLC: phospholipase C STAT: signal transducers and activators of transcription References Grandis JR, Sok JC: Signaling through the epidermal growth factor receptor during the development of malignancy. Pharmac...
Blood was immediately collected via cardiac puncture. Select organs were harvested, rinsed and dried to remove excess water. Bound activity was measured using a gamma counter. Activity measurements were background- and decay-corrected to the time of counting. The tissue uptake, expressed as % ...
View PDFView articleView in ScopusGoogle Scholar 46. T.K. Sundaresan, L.V. Sequist, J.V. Heymach, et al. Detection of T790M, the acquired resistance EGFR mutation, by tumour biopsy versus noninvasive blood-based analyses Clin Cancer Res, 22 (5) (2016), pp. 1103-1110 View in Scopus...