However, it can be difficult to obtain sufficient lung tumor tissue for testing. In such cases, a new blood test can be used instead, suggest the results from a "real world" study presented last week at the 2015
4、A Mini KitDxS EGFR Mutation Test Kit (DxS,Manchester, UK)48.2%95.4%90.0%68.1%73.5%Jie Wang2744YesPlasmaQIAamp DNA Mini KitDHPLC68.4%83.4%70.0%82.3%80.0%Britta Weber3196NoPlasmacobas DNA Sample Preperation KitARMS cobas EGFR Blood Test60.7%96.4%73.9%93.5%91.3%NCT012039174652YesPlasmaQIAamp ...
专用采血管含有EDTA抗凝剂及防细胞裂解的保护剂,保护剂使血液中的血细胞膜固化,防止细胞基因组DNA的释放并使污染的DNA酶变性失活,保持血浆cfDNA稳定1周。常用的cfDNA采血管包括Streck的cfDNA BCT Collection Tube,罗氏的Cell-Free DNA Collec...
EGFR检测血浆优于血清-周彩存.pdf,Trans la t iona l Onco logy Volume 7 Number 3 June 2014 pp. 341–348 341Peripheral Blood for Epidermal Growth Factor Receptor Mutation Detection in Non-Small Cell Lung Cancer PatientsXuefei Li*,1, Ruixin Ren?,1, Shengxiang
All patients had EGFR 20ins documented by local testing at enrollment, 143 of whom (95.3%) were further confirmed by central testing on tumor tissue samples (n = 143) and/or paired peripheral blood samples (n = 117). A total of 38 distinct EGFR 20ins variants were identified (...
Molecular testing in non–small cell lung cancer (NSCLC) is commonly limited by inadequate tumor sample. Plasma cell-free DNA (cfDNA) genotyping as a complementary test is specific but only moderately sensitive. Genotyping of cfDNA in pleural and pericardial effusion (PE-cfDNA) can further optimize...
Möglicherweise ist der verwendete Test hier nicht spezi sch genug. Friederike Klein Mayo-de-las-Casas C et al. Large scale, prospecti- ve screening of EGFR mutations in the blood of advanced NSCLC patients to guide treatment de- cisions. Ann Oncol. 2017;28(9):2248-55. kurz notiert ...
et al. Development and clinical utility of a blood-based test service for the rapid identification of actionable mutations in non-small cell lung carcinoma. J. Mol. Diagn. 19, 404–416 (2017). Article CAS PubMed Google Scholar Frampton, G. M. et al. Development and validation of a ...
We conducted an exploratory analysis to inform the clinical utility of EGFR mutation testing in blood cell-free DNA using the cobas (R) EGFR Mutation Test v2.Wu, Yi-LongLee, VictorLiam, Chong-KinLu, ShunPark, KeunchilSrimuninnimit, VichienWang, JieZhou, CaicunAppius, AnitaButton, Peter...
from the blood, balance fluids, control the production of red blood cells, and more. Estimated glomerular filtration rate (eGFR) is one of the primary diagnostic methods for detecting and managing kidney diseases. To find the eGFR, healthcare professionals use a blood test and a special ...