结果显示与对照组相比,Il-4rαfl/flClec4f-Cre+/-小鼠肝脏中磷酸化(p)-表皮生长因子受体(p-EGFR)水平降低,表明肝巨噬细胞中的IL-4/IL-4Rα信号可以调节一种或多种EGFR配体。在IR损伤后第3天从Il-4rαfl/flClec4f-Cre+/-...
WB IP IHC IF F Western blot analysis of extracts from various EGFR expressing cell lines, showing the specificity of detection of mutant EGFR (E746-A750del) protein, using EGF Receptor (E746-A750del Specific) (D6B6) XP® Rabbit mAb (upper), and total EGFR control antibo...
免疫印迹 (WB) 1:1,000-1:5,000 - 免疫细胞化学 (ICC/IF) 1:50-1:200 - 酶联免疫吸附实验 (ELISA) 0.125-0.25 µg/mL - 产品规格 种属反应 Human 宿主/亚型 Mouse / IgG, kappa 分类 Monoclonal 类型 Antibody 克隆号 9A1 抗原 Recombinant Human EGF ...
EGF (Epidermal growth factor) exerts its actions by binding to the EGF Receptor, a 170 kDa protein kinase. Activation of EGFR initiates diverse cellular pathways in response to toxic environmental stimuli, or to EGF binding to the receptor, the EGFR forms homo- or heterodimers with other family...
人表皮生长因子(EGF)是6-kDa的蛋白质,具有53个氨基酸残基和三个分子内二硫键,通过与细胞表面的同源受体EGFR结合,可以刺激细胞生长、分化和存活。EGF在体内和体外刺激各种表皮和上皮组织的生长,在细胞培养中刺激一些成纤维细胞的生长。这刺激配体诱导的二聚化,激活受体的固有蛋白酪氨酸激酶活性。
When EGF binds to its receptor (EGFR), it activates intracellular signaling pathways that lead to DNA synthesis and cell proliferation. EGF is naturally present in various tissues and body fluids, including saliva, urine, and milk. It is primarily synthesized in the submandibular glands and ...
产品应用 WB, ICC, IHC-P, IHC-F, ELISA 规格 100ug 标记物 未标记 价格 请咨询当地代理商 浓度200ug/ml 克隆类型 多克隆 宿主 Rabbit,兔 关键字:大鼠表皮生长因子EGF抗体 公司简介 上海研卉生物科技有限公司是一家专业经营生物、仪器、试剂、耗材的公司,在广大用户的帮助和支持下,经过不懈的努力, 已成为国...
Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.,online information:Epidermal growth factor entry,similarity:Contains 9 EGF-like domains.,similarity:Contains 9 LDL-receptor class B ...
Register a free CiteAb account today to view images used in this publication. Sign inorRegister for free 3 productsreferenced in this paper (ab15669)Anti-EGFR antibody an Antibody byAbcam(Product has been discontinued) Applications: WB(1:250) ...
signaling activation (2). Phosphorylation of EGFR at specific serine and threonine residues attenuates EGFR kinase activity. EGFR carboxy-terminal residues Ser1046 and Ser1047 are phosphorylated by CaM kinase II; mutation of either of these serines results in upregul...