Effects of ricin poisoning depend on whether ricin was inhaled, ingested, or injected. Ricin poisoning can eventually lead to multiple organ failure, leading to death within 36-72 hours of exposure, depending on the dosage of ricin and mode of exposure. There is no antidote for ricin; hence,...
For this reason, we developed ricin-specific antibodies that were tested in a murine model of ricin poisoning for use as antidotes against symptoms of ricin poisoning. Methods. Mice were poisoned with a lethal dose of ricin (5 渭g) and their temperature and general condition were monitored for...
Active immunization after passive monoclonal antibody and ricin toxin challenge: P. V. Lemley and D. C. Wright (Pathophysiology Division, U.S. Army Medical Research Institute of Infectious Diseases, Ft. Detrick, Frederick, MD 21702, U.S.A.). Toxicon, Volume 30, Issues 5–6, May–June 199...
infecting different parts of the body.Drugsthat control and eradicate these bacteria are called antibiotics. Levofloxacin is an antibiotic that stops multiplication of bacteria by preventing the reproduction and repair of their genetic material, DNA. It is in a class of antibiotics called fluoroquinolone...
Ricin is a highly toxic protein present in the seeds of castor (Ricinus communis), grown principally as a source of high quality industrial lubricant. Because of the past use of ricin for intentional poisoning, there is a need for analytical methodology to detect ricin in food matrices. Ground...
Abrin is a plant glycoprotein toxin from the seeds of Abrus precatorius, and shares the structure and properties with ricin. Abrin is highly toxic, with an estimated human fatal dose of 0.1-1 mu g/kg, causing death after accidental and intentional poisoning. It is a potent toxin warfare ...
Its performance was evaluated in terms of affinity for ricin, neutralization capacity, and therapeutic effects in cellular assays and a mouse model of ricin poisoning. Results: ARMAN exhibited a uniform morphology with an average particle size of 217 nm and demonstrated significantly enhanced affinity ...