Disrupting the circadian clock: genespecific effects on aging, cancer, and other phenotypes EA Yu,DR Weaver 被引量: 0发表: 2010年 Disruption of the circadian clock due to the Clock mutation has discrete effects on aging and carcinogenesis The mammalian circadian system has been implicated in the...
Last but not least, ALAN profoundly affected taxonomic compositions, species diversity and community structure of intestinal microbiota of birds. We concluded that ALAN may cause bird health damage by disrupting circadian rhythm, inhibiting melatonin release and altering intestinal microbiota. Melatonin ...
Overall, the effects of ALAN on organisms are multifaceted, including influencing physiology and behavior, altering when and how organisms reproduce, and disrupting circadian rhythms and annual cycles, and these effects may have far-reaching consequences for entire ecosystems. More research is therefore ...
Mn ++ does not appear to be producing phase shifts by disrupting the flux of Ca ++ across the plasma membrane since changing such fluxes by either raising extracellular Ca ++ (50 mM) or lowering extracellular Ca ++ with EGTA (Ca ++ <10 7 M) did not cause phase shifts in the rhythm. ...
“circadian rhythm signaling”, all of which have been associated with ASD. Similarly, “glutamate receptor signaling” and “axonal guidance signaling” were also present among the top canonical pathways significantly associated with DEGs in the female hippocampus (P-value < 0.05; Supplementary ...
Furthermore, we showed that MS has no effect on the circadian rhythm of activity by analysing it for four consecutive days. Social proximity, defined as the distance between individuals during social interactions, depends on the social relationships between individuals, not only in humans, but also...
circadian rhythms would be expected to drift and become desynchronised. The result, as discussed below in the sub-section ’Disrupting the clock’, will be a weakened health status of the patient. Light does more than regulate the timing of circadian rhythms – it also has a direct effect ...
Multiple endocrine neoplasia (MEN) refers to a hereditary disease wherein one or more of the endocrine glands are overactive or ...
This finding reflects the toxic effects of imidacloprid on bees, which attempt to increase detoxification capacity to compensate for the defense defect caused by imidacloprid disrupting antioxidant capacity. Given that melatonin has been found in this study to contribute to redox homeostasis and enhance ...
Bisphenol A (BPA) is a well-known for endocrine-disrupting chemical (EDC) and is one of the highest amounts of chemicals produced worldwide. Some countries restrict the use of BPA, which is widely used in the production of a variety products. Considering the toxicity and limitations on use...