The interplay of effector and regulatory T cells in cancer . Curr Opin Immunol (2015) 33C :101–11.10.1016/j.coi.2015.02.003 [ Cross Ref ]Roychoudhuri, R., R.L. Eil, and N.P. Restifo, The interplay of effector and regulatory T cells in cancer. Curr Opin Immunol, 2015. 33: p....
The transcriptional regulator Blimp1 plays crucial roles in controlling terminal differentiation in several lineages. In T cells, Blimp1 is expressed in both effector (Teff) and regulatory (Treg) cells, and mice with T cell-specific deletion of Blimp1 (Blimp1CKO mice) spontaneously develop severe ...
Here, we show that the frequency of PD-1+CD8+ T cells relative to that of PD-1+ regulatory T (Treg) cells in the tumor microenvironment can predict the clinical efficacy of programmed cell death protein 1 (PD-1) blockade therapies and is superior to other predictors, including PD ligand...
Regulatory T Cells Sequentially Migrate from Inflamed Tissues to Draining Lymph Nodes to Suppress the Alloimmune Response - ScienceDirect To determine the site and mechanism of suppression by regulatory T (Treg) cells, we investigated their migration and function in an islet allograft model. ... Z...
Critically, RelB within APCs was required for the expansion of donor helper T cell type 1 (Th1) effectors and subsequent alloreactivity, but not the peripheral expansion or function of donor FoxP3+ regulatory T cells. These data suggest that the targeted inhibition of nuclear RelB translocation...
T-regulatory cells and TH17 cells in peri-silicone implant capsular fibro- sis. Plast Reconstr Surg... Dolores,Wolfram,Evelyn,... - 《Plastic & Reconstructive Surgery》 被引量: 57发表: 2012年 LP26: T-REGULATORY CELLS AND TH17 CELLS IN PERI-SILICONE-IMPLANT CAPSULAR FIBROSIS Wolfram D, Ra...
我要写书评 Effector and Regulatory Cd4 T Cells During Mycobacterium Tuberculosis Infection.的书评 ··· ( 全部0 条 ) 论坛 ··· 在这本书的论坛里发言 + 加入购书单 谁读这本书? ··· 二手市场 ··· 在豆瓣转让 手里有一本闲着? 订阅关于Effector and Regulatory Cd4 T Cells Durin...
In cellular immunology the critical balance between effector and regulatory mechanisms is highlighted by serious immunopathologies attributable to mutations in Foxp3, a transcription factor required for a major subset of regulatory T (Tr) cells1,2,3. Thu
摘要: A healthy immune system requires a balance between effector T (TE) cells that mount immune responses, and regulatory T (TR) cells that prevent them. Understanding this balance requires knowing how theDOI: 10.1007/978-1-4419-7725-0_14 被引量: 2 ...
T淋巴细胞抗原细胞活素类The naive CD4 T cell is a multipotential precursor with defined antigen recognition specificity but substantial plasticity for development down distinct effector or regulatory lineages, contingent upon signals from cells of the innate immune system. The range of identified effector...