HIV prevention interventionmathematical modelcost-effectivenessBackground. Long-acting injectable antiretrovirals such as rilpivirine (RPV) could promote adherence to preexposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) prevention. However, the cost-effectiveness of injectable PrEP is unclear....
Recent trials report the short-term efficacy of tenofovir-based pre-exposure prophylaxis (PrEP) for prevention of human immunodeficiency virus (HIV) infection. PrEP's long-term impact on patient outcomes, population-level transmission, and cost-effectiveness remains unknown. We linked data from recent...
Context. - Oral HIV pre-exposure prophylaxis (PrEP) has been available and fully reimbursed for people at high risk of sexually acquired HIV infection in France since January 2016. Objective. - To evaluate the roll-out of PrEP use in France and its real-life effectiveness. The main results ...
We constructed a dynamic compartmental model of HIV infections among MSM in South Korea to assess the cost-effectiveness of PrEP for HIV prevention within this population (Fig. 1). The model estimated HIV prevalence, incidence, quality-adjusted life-years (QALYs), and healthcare cost of PrEP ...
However, none of the included interventions were found to be effective for reducing unsafe injection practices among people who inject drugs. HIV prevention interventions in Nepal have effectively reduced risky behaviours among female sex workers, men who have sex with men and transgender over the ...
of evidence generated over the last three years, showingCAB LAfor PrEP is a highly effective option for HIV prevention. We believe long-acting options have the potential to be transformative in increasing uptake among a broad range of people that could benefit from PrEP and are critical to...
IntroductionA vaginal ring containing dapivirine is effective for HIV prevention as pre‐exposure prophylaxis (PrEP). We evaluated the potential epidemiological impact and cost‐effectiveness of dapivirine vaginal ring PrEP among 22‐ to 45‐year‐old women in KwaZulu‐Natal, South Africa....
3SouthAfricanCentrefor EpidemiologicalModellingandAnalysis(SACEMA),DST/NRFCentreofExcellenceinEpidemiologicalModellingandAnalysis,StellenboschUniversity,Stellenbosch,South Africa Abstract Background:Mathematicalmodelershavegivenlittleattentiontothequestionofhowpre-exposureprophylaxis(PrEP) mayimpactonageneralizednationalHIV...
Use of a risk scoring tool to identify higher-risk HIV-1 serodiscordant couples for an antiretroviral-based HIV-1 prevention intervention Antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) reduce HIV-1 transmission within heterosexual HIV-1 serodiscordant couples. Prioritizing c... EM...
doi:10.1111/add.13597Commentary to: 'PrEP is not ready for our community, and our community is not ready for PrEP': pre-exposure prophylaxis for HIV for people who inject drugs and limits to the HIV prevention responseBrandonDepartmentD.DepartmentL.Department...