Large White pigs were used to investigate the effects of acetaminophen (paracetamol) on normal kidneys or those with an existing renal papillary necrosis. Pairs of young female animals were treated with either a single iv dose of 50 mg/kg 2-bromoethanamine (BEA), 100 mg/kg/day acetaminophen...
Stimulatory effect of paracetamol on chicken growth. ANALGESIC drugs, e.g. aniline derivatives, have been reported to increase growth hormone (STH) activity in normal female rats (Zor et al., 1965a). Paraceta... S Dikstein,U Zor,D Ruah,... - 《Poultry Science》...
kidneyParacetamol (5 mmol kg(-1), i.p.) caused liver damage in rats as indicated by increased plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT) and glutamate dehydrogenase (GDH) activities. No change in plasma bilirubin or creatinine was noted. An equimolar dose of nitro...
The effects of hepatic and renal damage on paracetamol metabolism and excretion following overdosage.: A pharmacokinetic study Summary1The kinetics of paracetamol metabolism and excretion were studied in 41 patients following overdosage. Acute hepatic necrosis developed in 23 patients and in 3 of these...
Analgesia during admission was achieved with paracetamol 1 g every eight hours and dexketoprofen every eight hours intravenously. Systemic or topical antibiotics were not routinely administered postoperatively. The wounds were examined every day by a surgeon until discharge. Drains were removed before ...
Protective effects of pineapple (Ananas comosus) on liver and kidney of Wistar rats intoxicated with Doliprane Effect of pineapple (Ananas comosus) on liver and kidney detoxication was studied in Wistar rats. Rats were treated with paracetamol at the dose of 2 g/kg ... TJ Dougnon,TM Kpodek...
1 In 2018, ankle (tibiotalar) osteoarthritis was estimated in a UK-based study to affect approximately 3.4% of adults.2 Younger active patients with ankle osteoarthritis have reduced quality of life, comparable to people with hip osteoarthritis, kidney failure, and congestive heart failure.3,4 ...
The effect of several nitric oxide releasing-non-steroidal anti-inflammatory drugs (NO-NSAID) and nitroprednisolone on blood vessel relaxation in vitro and in vivo was studied. Nitroflurbiprofen (NOF; EC 50 , 688.8±93.8 M ), nitroaspirin (NOA; EC 50 , 57.9±6.5 M ), nitroparacetamol (NO...
Although paracetamol is recommended worldwide as a first-line pain reliever for patients with dementia in nursing homes, there are limited reports on its analgesic effects [9]. Several studies have also evidenced that elderly persons with dementia are prescribed fewer NSAIDs and other anal- gesics...
use of BP-lowering or other medication with direct cardiovascular influences, secondary hypertension, and history of coronary artery disease, stroke, heart failure, valvular heart disease, diabetes, chronic kidney disease, alcohol or substance abuse, psychiatric illnesses, or other heart rhythm than sinu...