ACUTE kidney failureBLOOD plasma substitutesROUTINE diagnostic testsVOMITINGACETAMINOPHENACUTE kidney tubular necrosisDISEASE complicationsBackground: Paracetamol is a widely used analgesic and antipyretic. Paracetamol-induced hepatotoxicity is well known, but nephrotoxicity without hepatotoxicity is rarely seen. ...
Paracetamol poisoning and the kidney. Nephrotoxicity is less common than hepatotoxicity in paracetamol overdose but renal tubular damage and acute renal failure occur even in the absence of hep... AF Jones,JA Vale - 《Journal of Clinical Pharmacy & Therapeutics》 被引量: 101发表: 2010年 Scottish...
After an overdose serious hepatic impairment, even fulminant hepatic failure may occur. Acetaminophen toxicity also affects the kidney, pancreas and heart muscle. The treatment is based on the reduction of acetaminophen absorption with the aid of gastric lavage and active coal administration, and on ...
The drug does not irritate the stomach, as ASPIRIN does, but overdose causes liver and kidney damage and may cause death from liver failure. 15 g or more is potentially serious. The victim remains well for a day or two and liver failure develops between the third and fifth day. The drug...
If sensitivity reaction occurs, discontinue use of paracetamol. If pain persist more than 10 days and arthritic and rheumatic condition affecting children, immediately consult physician. If patient have been diagnosed with liver or kidney impairment, seek medical advice before taking medication. If sympt...
The patient was unsure which NSAID had caused her acute kidney failure, and it was not documented in her medical history. Discussion Analgesic nephropathy Chronic pain is a treatable condition that at any one point in time affects 20%–46% of community-dwelling older adults and 28%–73% of ...
It is metabolized primarily in the liver. Excessive use of paracetamol can damage multiple organs, especially the liver and kidney. An overdose causes a glutathione deficiency. The reactive metabolite may then cause hepatocellular damage and necrosis leading to acute liver failure. People must ...
[Acute kidney failure caused by paracetamol poisoning]. Paracetamol poisoning is manifested by hepatotoxicity, but acute renal failure is very rare, especially when there is no fulminant hepatic damage with ence... JL Herrero,I Castellano,JR Gómez-Martino,... - 《Nefrología Publicación Oficial De...
Pyroglutamic acidosis is a rare cause of high anion gap metabolic acidosis. Most cases of paracetamol related pyroglutamic acidosis are described in malnourished women and patients with kidney/liver failure, alcohol use or severe sepsis. In this report,
Those we have tell us that paracetamol use is associated with increased rates of death, heart attack, stomach bleeding and kidney failure. Paracetamol isknown to cause liver failure in overdose, but it also causes liver failure in people taking standard doses for pain relief. ...