DUOX2DUOX2dual oxidase-like domains 2, flavoprotein NADPH oxidase, LNOX2, NADH / NADPH thyroid oxidase p138-tox, NADPH oxidase / peroxidase DUOX2, NADPH thyroid oxidase 2, nicotinamide adenine dinucleotide phosphate oxidase, P138(TOX), P138-TOX, THOX2 ...
The results showed that different EF-hand domains had unique structures and thermodynamic properties, which determined their roles in assembly and function, and improved our understanding of EF-hand protein. Keywords: EF-hand protein, functional domain, secondary structure, tertiary structure, dynamics ...
1)EF-hand domainsEF-hand结构域 2)ESVEF 1.Objective:To compare the prognostic significance of Chronotropic function(85%of maximal age-predicted heart rate,heart rate reserve),exercise myocardial perfusion tomography(MPI), post-exercise end-systolic volume(ESV)and left ventricular ejection fraction(EF...
EF-hand domains are involved in the differential cellular distribution of dystrophin Dp40doi:10.1016/j.neulet.2015.05.038DystrophinDp40EF-handsSubcellularlocalizationβ-dystroglycanPC12cellsSite-directedmutagenesisDp40 is the shortest DMD gene product that has been reported to date. It is encoded by ...
We propose that conformational change of Ca2 + sensor EF-hand domains depends on solvation energetics, Ca2 + binding to promote the full open form, Ca2 + depleted state conformational dynamics, and the chemical properties of the molecules nearby key residues such as those at positions 41 and 75...
Simple purification protocols provide high yields of homogenous proteins: dialysis and DEAE-cellulose chromatography for domains I-II and III-IV or ammonium sulfate precipitation and octyl-Sepharose chromatography for domain V-VI. To our knowledge, this is the first report of the expression of an ...
One branch represents efhd and aif1, both of which gene products exhibit EF-hand domains (one in AIF-1 and two in EFhd). The other branch represents a gene encoding a unique protein in C. elegans (WP:CE38519) (Figure 2, bottom) that consists only of a coiled-coil domain at the ...
A database of nonredundant structures of EF-hand domains--i.e., pairs of helix-loop-helix motifs--has been assembled, and the six angles among the four helices re-determined. A principal component analysis of these angles allows us to use two such components (and ) to describe the system...
The Role of EF-hand Domains and C2 Domain in Regulation of Enzymatic Activity of Phospholipase Cζ Sperm-specific phospholipase C-zeta (PLCzeta) induces Ca2+ oscillations and egg activation when injected into mouse eggs. PLCzeta has such a high Ca2+ sens... Z Kouchi,T Shikano,Y Nakamura...
We have analyzed the conformations of EF-lobes, adjacent pairs of EF-hand domains, in a coordinate system based on the approximate two-fold ( z ) axis that... H Kawasaki,RH Kretsinger - 《Proteins-structure Function & Bioinformatics》 被引量: 11发表: 2015年 加载更多来源...