Driven by an N-terminal 伪/尾-hydrolase-folded domain with a protruding interaction helix, EDS1 assembles with two homologs, phytoalexin-deficient 4 (PAD4) and senescence-associated gene 101 (SAG101). The resulting heterodimers are critical for EDS1 function and structurally well characterized. ...
Mutational analysis of the EDS1-SAG101 heterodimer and a derived EDS1-PAD4 structural model shows that EDS1 signals within mutually exclusive heterocomplexes. Although there is evolutionary conservation of α/β hydrolase topology in all three proteins, a noncatalytic resistance mechanism is indicated....
An EDS1-SAG101 complex interacts with NRG1, and EDS1-PAD4 with ADR1, in an immune-activated state. NRG1 requires an intact nucleotide-binding P-loop motif, and EDS1 a functional EP domain and its partner SAG101, for induced association and immunity. Thus, two distinct modules (NRG1/...
在Arabidopsis,三个像脂肪分解酵素的管理者, SAG101, EDS1,和 PAD4,抵抗下游地行动联系蛋白质的防卫发信号.尽管在关於生命的应力的 SAG101, EDS1,和 PAD4 的角色广泛地被学习了,很少在对不能生活的压力的植物回答对他们的功能被知道.这里,我们证明 SAG101, EDS1,和 PAD4 涉及在 Arabidopsis 冻结忍耐的规定...
In Arabidopsis, three lipase-like regulators, SAG101, EDS1, and PAD4, act downstream of resistance protein-associated defense signaling. Although the roles of SAG101, EDS1, and PAD4 in biotic stress have been extensively studied, little is known about their functions in plant responses to ...
Mutational analysis of the EDS1-SAG101 heterodimer and a derived EDS1-PAD4 structural model shows that EDS1 signals within mutually exclusive heterocomplexes. Although there is evolutionary conservation of alpha/beta hydrolase topology in all three proteins, a noncatalytic resistance mechanism is ...
EDS1PAD4SAG101ETIimmunityplantSUMMARY Arabidopsis pathogen effector‐triggered immunity (ETI) is controlled by a family of three lipase‐like proteins (EDS1, PAD4, and SAG101) and two subfamilies of HET‐S/LOB‐B (HeLo)‐domain "helper" nucleotide‐binding/leucine‐rich repeats (ADR1s and ...
(2015) Disruption of the Arabidopsis defense regulator genes SAG101, EDS1, and PAD4 confers enhanced freezing tolerance. Mol. Plant 8: 1536-1549.Chen QF, Xu L, Tan WJ, Chen L, Qi H, Xie LJ, Chen MX, Liu BY, Yu LJ, Yao N, Zhang JH, Shu W, Xiao S (2015) Disruption of the...
An EDS1-SAG101 complex interacts with NRG1, and EDS1-PAD4 with ADR1, in an immune-activated state. NRG1 requires an intact nucleotide-binding P-loop motif, and EDS1 a functional EP domain and its partner SAG101, for induced association and immunity. Thus, two distinct modules (NRG1/...
Disruption of the Arabidopsis Defense Regulator Genes SAG101, EDS1, and PAD4 Confers Enhanced Freezing Tolerance拟南芥 抗冻性 防卫基因 非生物胁迫 中断 冻结温度 突变体 L系统vip分子植物(英文版)Qin-Fang Chen[1,3] Le Xu[1,3] Wei-Juan Tan[1,3] Liang Chen[1] Hua Qi[1] Li-Juan Xie[1] ...