Our previous study showed that IPF lung-ECM had increased tissue density and stiffness in comparison to healthy lung-ECM with several differentially expressed matrix proteins, which was also seen in newly synthesized proteins from repopulated acellular lung tissue.Aims: We aim to describe how ...
Image-based finite element mechanical models predicted an increase in the transverse relative to longitudinal (muscle fiber direction) stiffness, with the stiffness ratio (transverse/longitudinal) increased in the mdx model compared to the WT at three and six months. This study highlights that the ...