For effective use in regenerative medicine and cell therapy, chemically defined, non-xenogeneic, reproducible, and scalable culture conditions are required. This is typically achieved by adding specific ECM components into the culture system, providing a stable environment essential for stem cell survival...
These data suggest that uncontrolled integration of confluence-dependent signaling, might favor skin disorders, including tumorigenesis, not only by promoting cell hyperproliferation, but also by altering protease activity and deposition of ECM components....
Our results indicate that in the sea urchin embryo the appropriate contact of ectodermal cells with outer ECM components is essential for the correct morphogenesis of inner mesodermal structures. 展开 关键词: sea urchin embryo ECM protein morphogenesis skeletogenesis pigment cells ...
The immunolabel was most intense in the fibronectin-like protein, followed by the type IV collagen-like protein and weakest in the laminin-like protein. From an evolutionary point of view, this kind of distribution of ECM components, primarily found in intracellular regions, seems to reflect a ...
The immunolabel was most intense in the fibronectin-like protein, followed by the type IV collagen-like protein and weakest in the laminin-like protein. From an evolutionary point of view, this kind of distribution of ECM components, primarily found in intracellular regions, seems to reflect a ...
Components ECM Array Plate: (PN: 90652) One 96-well plate with 12 strips. Each 8-well strip consists of 7 different human, ECM protein-coated wells (Collagen I, Collagen II, Collagen IV, Fibronectin, Laminin, Tenascin, Vitronectin) and one BSA-coated well (negative control). See the plat...
Recently, protein therapies that replace components of the defective myomatrix or enhance muscle and/or extracellular matrix integrity and function have been explored. Preclinical studies for many of these biologics have been promising in animal models of these muscle diseases. This review aims to ...
ECM components [101]. The end result of the involvement of such a large range of signaling molecules is the activation of several groups of intracellular kinases such as Src, Src-like protein kinases (Hck and Fgf) and again FAK with convergence on the extracellular regulated kinase (ERK)1/2...
ECM Select® Array Kit Ultra-36 is an overnight extracellular matrix screening array which helps you find the best extracellular matrix (ECM) protein for your cells. This product has 36 human ECM conditions that are each printed as 9 replica
Future studies will need to define the detailed function of specific pdgfrb+ cell-derived matrix components in promoting axonal growth. In this context, it would be interesting to utilize the larval zebrafish SCI model to dissect the mechanisms mediating the growth-inhibitory properties of Lum and ...