Department of Cardiologythe Fifth Affiliated Hospital of Xin Jiang Medical UniversityUrumchi 830001Journal of cellular biochemistry.Wang, J. et al. The role of c-SKI in regulation of TGF-β-induced human cardiac fibroblast proliferation and ECM protein expression. J. Cell Biochem. 118, 1911-1920 ...
This script allows the identification of ECM genes/proteins in datasets and annotates these genes/proteins according to matrisome divisions (core matrisome or matrisome-associated) and categories (ECM glycoproteins, collagens and proteoglycans, for core matrisome genes, ECM-affiliated, ECM regulators and...
The activation of cancer-associated fibroblasts (CAFs) is a key event in tumor progression, and alternative extracellular matrix (ECM) proteins derived from CAFs induce ECM remodeling and cancer cell invasion. Here we found that miR-200 s, which are generally downregulated in activated CAFs in ...
On the other hand, cell contact with extracellular matrix (ECM) proteins also plays a critical role in regulating hMSC osteogenesis [29-31]. Since ECMP (extracellular matrix receptor) is highly enriched in our enrichment analysis and the interaction between ECMP and osteoporosis hasn't been ...
Frozen human breast or liver cancer sections Second Affiliated Hospital of Army Medical University N/A Frozen sections from mice tumor tissues This paper N/A BMDCs from bone marrow This paper N/A Spleens from mice This paper N/A Chemicals, peptides, and recombinant proteins Mncl2 Macklin Cat...
As a mediate of Adamts1's function, ECM proteins and FAK–ERK pathway have also been assessed in miR-181d-Adamts1 axis. Accordingly, miR-181d overexpression increased the expres- sion of Thbs1, Fibronectin, Col1α1, and Col5α1, while co- overexpression of Adamts1 reversed this pattern...
The high expression level of ECM proteins or genes in breast tumor tissues may provide new ideas for cancer treatment. We think that these genes and pathways may be potential markers for breast cancer, but the mechanisms of tumorigenesis and development need to be verified in further experiments....
[33]. Here, we demonstrated that autophagosome numbers and expressions of autophagy proteins were exaggerated when MDA-MB-231 cells were treated with the combination of lapatinib and erastin, accompanied with enhanced intracellular ferrous iron. Ferritin was degraded in lapatinib and erastin co-treated...
“Abandoned Reminder” unravels its story from whispering electronics, as Taborn narrates a ballad-turned-trip down a stairway of psychological proportion. Such changes are indicative of an overall constitution, which by suggestion of an unusual fluidity activates proteins in underused listening muscles....
TA is a polyphenolic compound that strongly binds to proteins via hydrophobic and hydrogen bonds [48]. Many studies have been conducted to utilize protein-binding TA for its therapeutic effects [49,50]. Recently, Mao et al. found that TA can bind to the two most abundant proteins, voltage-...