The Role of Ecdysteroid 22-Kinase in the Accumulation of Ecdysteroids in Ovary of Silkworm Bombyx mori. Yoichi Ito,Haruyuki Sonobe. Annals of the New York Academy of Sciences . 2009Ito Y, Sonobe H. The Role of Ecdysteroid 22-Kinase in the Accumulation of Ecdysteroids in Ovary of Silkworm ...
Ecdysteroids are polyhydroxylated sterols, and are widespread in the plant and animal world. To date, over 520 ecdysteroids have been isolated from natural sources. The most accessible and studied representative of this class of compounds is 20-hydroxyecdysone (20E)—a universal hormone for the de...
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Ecdysterone also causes an influx of calcium ions into the cells, which causes an increase in the phosphorylation of Akt. Akt is a protein kinase that mediates protein synthesis, so if ecdysterone increases its activity, then this could be the mechanism through which it enhances muscle growth.[...
preferential expression of five genes encoding proteins involved in Ca2+-signaling, such as Ca2+/calmodulin-dependent protein kinase II (CaMKII)19, which plays a central role in the synaptic plasticity that serves as a platform for learning and memory processes in many animal species20,21,22,23...
Stimulation of the PG by neuropeptides involves several signaling cascades, including a cAMP-dependent pathway, a classical mitogen-activated protein kinase cascade, and an S6 kinase pathway (3, 5, 6). These pathways control synthesis of ecdysteroids from dietary cholesterol or phytosterols via a ...
B. The insect neuropeptide PTTH activates receptor tyrosine kinase torso to initiate metamorphosis. Science 326, 1403–1405 (2009). 22. Nu¨sslein-Volhard, C. & Wieschaus, E. Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster I. Zygotic loci on the second ...
We also provide preliminary evidence that CG5644 encodes an ecdysteroid 22-kinase conserved across Diptera.Scanlan, Jack L.The University of Melbourne School of BioSciencesRobin, CharlesG3: Genes, Genomes, Genetics
The multidirectional activity of ecdysteroids has raised the question of how these compounds are able to affect that many processes. A plausible hypothesis is that ecdysteroids affect Akt/PKB (protein kinase B) pathway, an intracellular signaling cascade that plays a central role in mammalian cell ...