Analysis of single EBV-infected cells from tonsils of IM patients for rearranged immunoglobulin genes revealed two strategies of EBV for rapid and massive spread in the B cell compartment: the direct infection of many naive as well as memory and/or germinal center B cells and the expansion of ...
Infection of humans with Epstein-Barr virus (EBV) may cause infectious mononucleosis (IM). Analysis of single EBV-infected cells from tonsils of IM patients for rearranged immunoglobulin genes revealed two strategies of EBV for rapid and massive spread in the B cell compartment: the direct infecti...
most frequently of diffuse large B-cell lymphoma morphology and associated with Epstein-Barr virus (EBV) infection/reactivation. In this study the microenvironment of EBV(+) (n=23) and EBV(-) (n=9) post-transplant non-germinal center...
Analysis of single EBV-infected cells from tonsils of IM patients for rearranged immunoglobulin genes revealed two strategies of EBV for rapid and massive spread in the B cell compartment: the direct infection of many naive as well as memory and/or germinal center B cells and the expansion of ...
The cause of an Epstein-Barr virus infection or mono is the infection of circulating B cells by EBV and the body's response to the presence of the virus. Risk factors include intimate contact with body secretions (primarily mouth secretions but including other body fluids like those found in ...
13. Ok CY, Li L, Xu-Monette ZY, Visco C, Tzankov A, Manyam GC, et al. Prevalence and clinical implications of epstein-barr virus infection in de novo diffuse large B-cell lymphoma in Western countries. Clin Cancer R...
About 90% of adults worldwide are infected with Epstein-Barr virus, or EBV. The virus infects B cells (the white blood cells that make antibodies) and can contribute to B-cell-derived cancers, but in most people it remains dormant—a state scientists refer to as "latent infection"—for ...
NF- B p65/p50 signaling, and we provide evidence that BAX may be an important target of the antiapoptotic activity of LMP-1. Materials and methods Cells, plasmids, and inhibitory drugs The cell lines DG-75, 26 EBV-negative Akata (an Akata subclone that has ...
Epstein Barr virus (EBV) infection of human B lymphocytes in vitro results in immortalisation of the cells and augmented membranous expression of numerous B-cell activation molecules, including CD23. Other studies demonstrated that only those B lymphocytes which carry the surface CD21 (EBV receptor...
The ins and outs of EBV infection 来自 dx.doi.org 喜欢 0 阅读量: 36 作者:GC Faulkner,AS Krajewski,DH Crawford 摘要: Epstein-Barr virus (EBV) infects almost the entire adult population of the world. The success of this virus appears to be based on its ability to infect the B cell, ...