Molecular profiling of EBV associated diffuse large B-cell lymphoma. Leukemia. 2023 Mar;37(3):670-679. EBV-positive diffuse large B-cell lymphoma, not otherwise specified: 2022 update on diagnosis, risk-stratification, and management. Am J Hematol. 2022...
非特指型EBV阳性弥漫大B细胞淋巴瘤【Epstein-Barr virus (EBV)–positive diffuse large B-cell lymphoma, not otherwise specified (EBV+ DLBCL, NOS)】是一组相关疾病的统称,是不符合更特定EBV阳性疾病实体的诊断标准。该疾病被认为是由年龄相关的免疫抑...
EBV+ Diffuse Large B-Cell Lymphoma,NOS 查宏斌 更新时间:2018-11-17 09:58:00 概述: EBV感染引起的克隆性B细胞增生,多发生在50岁以上,但也见于年轻患者,无已知免疫缺陷或淋巴瘤病史,累及淋巴结(年轻患者)和结外组织(老年多见),临床表现为侵袭性,但年轻人预后较好。需除外其它EBV相关淋巴增生性疾病实体(如...
非特指型EBV阳性弥漫大B细胞淋巴瘤【Epstein-Barr virus (EBV)–positive diffuse large B-cell lymphoma, not otherwise specified (EBV DLBCL, NOS)】是一组相关疾病的统称,是不符合更特定EBV阳性疾病实体的诊断标准。该疾病被认为是由年龄相关的免疫抑制引起的,患者没有已知的免疫缺陷或既往EBV相关的淋巴组织增生性...
EB病毒(Epstein-Barr virus,EBV),又称人类疱疹病毒4型,属γ疱疹病毒科。1964年Epstein与Barr首次在Burkitt淋巴瘤(Burkitt’s Lymphoma,BL)中发现该病毒,并命名为EBV。全世界约有95%以上的人口曾感染EBV,绝大多是隐性感染,部分形成传染性单核细胞增多症、咽炎等急
InfectioninDeNovoDiffuseLargeB-CellLymphomain WesternCountries.ClinCancerRes;2023,20(9);2338–2349.3738老年EBV阳性DLBCL治疗尚无针对性旳治疗措施R-CHOP或CHOP仍是主要治疗措施硼替左米:体外证明能诱导EBV转化旳B细胞凋亡丙戊酸(valproicacid)或苯丁酸(arginine Butyrate)联合更昔洛韦:Bortezomib联合ganciclovir39Novelthe...
EBV-positive lymphomaimmune escapeimmunodeficiencylymphoproliferative disorderPD-L1Background Epstein‐Barr virus (EBV) is detected in a variety of B‐cell lymphomas (BCLs) and B‐cell lymphoproliferative disorders (B‐LPDs). Immunodeficiency has been considered to play a key role in the pathogenesis ...
Fig. 1. The classification scheme for EBV-associated lymphoproliferative disorders. DLBCL, diffuse large B-cell lymphoma; HHV8, human virus herpes 8; HIV, human immunodeficiency virus; NOS, not otherwise specified; PTLDs, posttransplant lymphoproliferative disorders. ...
10、 effects and can be applied and promoted in clinical.key words rituximab; diffuse large b cells; lymphoma; chemotherapy弥漫大b细胞淋巴瘤(diffuse large bcell lymphoma, dlbcl)是一种发病率较高的菲霍奇金 淋巴瘤(non-hodgkin's lymphoma, nhl) 1,其发病率占30%40%,其生物学行为属侵袭性, 但部分...
结外NK/T细胞淋巴瘤(鼻型)(Extranodal NK/T-Cell lymphoma, nasal type [ENKTCL-NT])是一种与 EB 病毒 (EBV) 感染相关的侵袭性恶性肿瘤,主要影响鼻腔或上呼吸道结构,预后不佳。ENKTCL-NT好发于亚洲和拉丁美洲男性,中位发病年龄为 46-60 岁,在这两个地区,ENKTCL-NT 约占非霍奇金淋巴瘤 (NHL) 的 3-...