EBF1 gene promotes the proliferation and inhibits the apoptosis of bone marrow CD34+ cells in patients with myelodysplastic syndrome through negative regulation of mitogen‐activated protein kinase axisbone marrow CD34+ cellscell apoptosiscell migration...
EBF1 (EBF transcription factor 1) 基因名:EBF1 别名:EBF,COE1,OLF1,O/E-1 基因ID:1879 Chromosome: (GRCh37)5Start:158122916End:158526788Strand: 信号通路: EBF1 基因突变与药物
Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants. 基因名: PDGFB 别名: IBGC5,PDGF-...
在MSC中条件性敲除Ebf1改变了它们的细胞组成、染色质结构和基因表达谱，包括粘附相关基因的表达减少。在功能上，基质特异性Ebf1失活导致HSC的粘附受损，从而导致静息性降低和骨髓输出减少。最值得注意的是，Ebf1缺陷的驻留HSC其细胞组成和染色质结构发生了变化，这些变化在连续移植中仍然存在。因此，BM小生境中的遗传...
表达矩阵可以下载:All high-throughput data in this study were deposited at the Gene Expression Omnibus (GEO) under seriesGSE127970(CAR, PαS RNA-seq and ATAC-seq), seriesGSE128089(HSC RNA-seq and ATAC-seq), and seriesGSE128743(single-cell RNA-seq). A web application for scRNA-seq data ...
Ensembl Gene IDENSG00000164330.17 Ensembl mRNA IDEBF1-201 包装清单: 产品编号产品名称包装 QH13517SHuman EBF1 qPCR Primer Pair1nmol each —说明书1份 保存条件: -20℃保存。建议复溶后进行适当分装,避免反复冻融。 注意事项: PCR扩增产物的长度可能会因基因转录后存在多种剪接形式而有所差异。
1 Ebf1 deficiency alters MSC composition and gene expression. a, Representative gating strategy used to identify and isolate CAR and PaS cells. b, Heat map depicting log2-transformed normalized expression of signature genes (rows) across the cells in each cluster (columns). Key genes are ...
Svati H Shah2,4, Redford B Williams1,3 and Elizabeth R Hauser2,4,6 We performed gene–environment interaction genome-wide association analysis (G × E GWAS) to identify SNPs whose effects on metabolic traits are modified by chronic psychosocial stress in the Multi-Ethnic Study of Atherosclerosi...
表达矩阵可以下载:All high-throughput data in this study were deposited at the Gene Expression Omnibus (GEO) under seriesGSE127970(CAR, PαS RNA-seq and ATAC-seq), seriesGSE128089(HSC RNA-seq and ATAC-seq), and seriesGSE128743(single-cell RNA-seq). A web application for scRNA-seq data ...
(-5T-B加强1惴吼比d暑dmlycc和巾呲ted.K巧words:E秘画I卜&盯vir咽;BNllFlgene;严0l【aryo酏exp嘲d∞V∞10r(踟1.,蹦脚,2008,12:0702)基金项目:福建省教育厅高等学校新世纪优秀人才支持计划项目(N㈣积研)・通讯作者 PDFWatermarkRemoverDEMO:Purchasefrom.PDFWatermarkRemovertoremovethewatermarkEB病毒(...