利用SwissTargetPrediction、SEA、PharmMapper数据库共筛选得到淫羊藿素作用靶点252个。通过DisGeNET、GeneCards、MalaCards数据库共筛选得到多发性骨髓瘤疾病靶点4 076个。将淫羊藿素作用靶点与多发性骨髓瘤疾病靶点进行Venn分析,见图1,两者共有143...
KEGG通路分析后,富集了三条信号通路,其中“钙信号通路”显著丰富,表明Cos处理影响了与Ca2+调节相关蛋白质的抗蛋白酶水解特性。从基因Cards数据库(https://www.genecards.org/)中检索血管收缩、脑缺血相关蛋白,使用维恩图对差异上调的蛋白...
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Here we show that RIG-I and NOD2 not only colocalize to cellular ruffles and cell-cell junctions, but that they also form a direct interaction that is mediated by the CARDs of RIG-I and multiple regions of NOD2. Moreover, we show that RIG-I negatively regulates ligand-induced nuclear ...
方法:检索中药系统药理学数据库与分析(TCMSP)数据库,查阅文献获得黄芪-当归潜在活性成分及作用靶点,通过GeneCards数据库、OMIM数据库、DDT数据库和Drugbank数据库获得糖尿病足的疾病潜在靶点;应用Metascape平台对潜在靶点进行基因本体(GO)富集分析和京都基因与基因组百科全书(KEGG)富集分析;运用String数据库和Cytoscape软件...
In 2010,Hwang,et al.proposed a 'DoS-resistant ID-based password authentication scheme using smart cards' as an improvement of Kim-Lee-Yoo's 'ID-based passw... F Wen - 《电子科学学刊(英文版)》 被引量: 0发表: 2011年 Mutations in the dihydrofolate reductase gene of trimethoprim-resistant...
In 1887, a German immigrant and businessman named John Heinlen established a settlement for San Jose's Chinese population that had been displaced from four previous Chinatowns. Having experienced anti-German sentiments during his family's time in the midwest, he understood the difficulties of estab...
一台机器只要装有该语言的编译器,就能够运行用高级语言编写的程序。A.正确B.错误的答案是什么.用刷刷题APP,拍照搜索答疑.刷刷题(shuashuati.com)是专业的大学职业搜题找答案,刷题练习的工具.一键将文档转化为在线题库手机刷题,以提高学习效率,是学习的生产力工具
查询OMIM （Online Mendelian Inheritance in Man ）、GeneCards 数据库获得疾病相关靶点基因，进而运用Cytoscape 软件构建药物活性分子-靶点基因作用网络，通过R 语言包clusterProfiler 进行基因本体（gene ontology ，GO ）功能注释和基于京都基因与基因组百科全书（Kyoto Encyclopedia of Genes and Genomes ，KEGG ）通路...
Messenger RNA was isolated from a bacteria and used to identify a specific gene. Which of the following techniques would be utilized for this process? A. Northern blotting B. Southern Blotting C. Western Blotting D. PCR 查看完整题目与答案 大理岩是由( )变成的 A. 砂岩 B. 石灰岩 ...