Objectives The objective of this study was to identify early symptoms of SLE from the patient perspective. Methods As approved by the local ethics committee, we conducted a cross-sectional survey of German SLE patients. An anonymous self-report questionnaire was published in the "Schmetterling" the...
due to its ambiguous symptoms which may not fully align with the classification criteria of established systemic lupus erythematosus (SLE).Nonetheless, this condition should not be underestimated due to its potential impact on major organ involvement and its t...
Because the variegated symptoms of SS are not always present at the same time, physicians and dentists sometimes treat each symptom individually, unaware that a systemic disease is present. In the past, people with SS were frequently misdiagnosed because their symptoms were considered minor or ...
for SLE, which is an antibody mediated disease. We note that pregnancy is documented to exert protective effects in AS, CD, MS, and RA, which areinflammatory diseases. In particular, there is overwhelming evidence to demonstrate that pregnancy is associated with improved symptoms in MS and RA....
All patients had mild skin symptoms with no systemic treatments that could have influenced the photoprovocation experiments. DLE patients included three males and seven females with an average age of 57 years (range 44–72). SCLE patients and the controls were all female with an average age of...
reluctant to participate if the fall was precipitated by an underlying medical condition – Patient 19 shared ““I felt so weak, I had this vertigo for two or three days before I came in, …so I was still suffering from that”, requesting activities be deferred until her symptoms improved...
Background: Systemic lupus erythematosus (SLE) exhibits a wide range of symptoms and signs, often including joint manifestations. Subclinical inflammatory ... S. Marsico,I. Carrión-Barberà,P. Corzo,... - Annals of the Rheumatic Diseases 被引量: 0发表: 2024年 The natural history of symptomat...
Recently, a B cell-targeted biological agent, belimumab, which explicitly inhibits the B cell activating factor (BAFF), has been shown to alleviate clinical symptoms and reduce the production of immunological abnormalities in SLE patients. Belimumab uses a single target and has been used for ...
Eighty-one percent of these patients were diagnosed with stage IV disease, 25% had an elevated lactate dehydrogenase (LDH) serum level, and 37% presented with B symptoms. In addition, of the 108 patients evaluable for the IPI,27 43% had a low-risk, 41% a low-intermediate, 11% a high...
In both primary and secondary SjS, the presenting symptoms of ocular surface dryness, corneal irritation and increased susceptibility to infection overlap with symptoms of simple keratoconjunctivitis sicca (KCS). Despite the potentially unique disease profile that is likely to be manifested in the tears...