proteomic analysis of serum or plasma has been challenging because of low protein concentrations and a wide dynamic range of protein abundances, resulting in low quantification precision, throughput, and limited proteome depth16,17,18. Recent advances in MS-based proteomics have greatly...
Although the strategies for early detection have developed rapidly in recent decades, they remain challenging due to the subtle symptoms in the initial stage of the primary tumor. Currently, tumor biomarkers, imaging, and specific screening tests are widely used in various cancer types; however, ...
All women were examined for STI-related symptoms and had vaginal swabs collected and stored for later STI testing. Vaginal swabs were tested for Trichomonas vaginalis (T.vaginalis), Chlamydia trachomatis (C. trachomatis), Neisseria gonorrhoeae (N. gonorrhoea) and herpes simplex virus-2 (HSV-2) ...
(raven colour progressive matrix™), an index regarding symptoms of attention disabilities and hyperactivity disorders (adhd) (conner's rating scales of 27 items) and internalizing and externalizing scores (99-item child behaviour checklist (cbcl) [ 6 , 8 ]. all these health parameters were ...
Comparison of A-SAA derived biomarker levels among hepatitis, LC, and HCC patients. A total of 166 serum samples from 40 hepatitis (indicated as H), 30 LC, and 96 HCC patients were measured and analyzed. (a) Total A-SAA. (b) A-SAA monomer. (c) A-SAA oligomer. The statistical anal...
These four biomarkers are differentially regulated between quiescent Mycobacterium tuberculosis (Mtb) infected individuals (non-progressors to TB disease) and Mtb-infected TB disease progressors 6 months before the onset of symptoms. Methods We enrolled samples from patients experiencing moderate-to-severe...
Conversely, STY infection has an incubation period of up to two weeks and results in systemic bacteremia with limited or no gastrointestinal symptoms. Comparative genomics between the two serovars reveals 480 STM-unique genes and 600-STY-unique genes [66]; notable STY genetic acquisitions include ...
Congenital hypothyroidism in humans leads to a syndrome termed cretinism [27], the apparent symptoms of which include ataxia and poor motor skills, indicating cerebellar defects. In PCs, TH is known to strongly promote differentiation of the elaborate dendritic tree and synapse formation. In ...
symptoms. We come up the hypothesis that whether there exist core targets at the genomic level which might regulate multiple pathways simultaneously. Chromosomal three-dimensional (3D) structure, comprising the switching of A or B compartments, reorganization of topologically associated domains (TADs), ...
ISAAC: Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Lancet. 1998, 351: 1225-1232. 10.1016/S0140-6736(97)07302-9. Google Scholar Asher MI...