Although several randomized clinical trials in the 1980s indicated a benefit from the use of in the treatment of early-stage , questions have remained regarding the optimal duration of drug administration. In 1982, the National Surgical Adjuvant Breast and Bowel Project (NSABP) initiated a randomize...
Find an Early-Stage Clinical TrialAn abstract is unavailable.Barbara Bronson Gray
The use of dual immune checkpoint inhibitors durvalumab (Imfinzi) and tremelimumab in combination with neoadjuvant chemotherapy showed promising clinical response without major adverse events (AEs) in patients with advanced-stage ovarian cancer, according to initial data from the ph...
A growing number of artificial intelligence (AI)-based clinical decision support systems are showing promising performance in preclinical, in silico evaluation, but few have yet demonstrated real benefit to patient care. Early-stage clinical evaluation is important to assess an AI system’s actual cli...
David Spigel, MD, and David H. Harpole Jr, MD, describe when adjuvant therapy is recommended in early stage NSCLC and discuss data from recent clinical trials of adjuvant therapy. This is a modal window. This video is either unavailable or not supported in this browser Error Code: MEDIA_...
Clinical trial shows no side effects from proton treatment for early stage breast cancer patientsPaxton, Annemarie
Boston, Mass., March 2, 2009-WorldCare Clinical, LLC (WCC), a leading imaging CRO for clinical trials in the pharmaceutical, biotechnology, and medical device industries, today introduced a new service offering to support sponsors conducting early-stage and Phase II clinical tria...
However, hyponatremia may also reflect a more advanced, otherwise undetected, stage of cancer in general. Further exploration of the etiology and the optimal cut-off value of hyponatremia should be considered in future studies and, more importantly, the role of hyponatremia as an eligibility ...
Table 1. FIGO Stage System. The decision of maintaining the clinical evaluation as the most important factor in staging was based on the knowledge that the highest rates of CC are reported in low-income countries where imaging can be challenging [21]. However, it is also known that staging...
Compared with significant differences in the low/medium tau population, this supports the hypothesis that a greater benefit from amyloid-lowering therapies may occur when initiated at an earlier disease stage. Similar to other amyloid-lowering drugs, and the phase 2 TRAILBLAZER-ALZ trial, amyloid-...