treatment- resistant depressionDysthymia is a psychopathological construct historically described and often reconsidered through the centuries. Its first description is dated back to 400 b.C., when Hippocrates proposed his theory about the 'black bile' and the melancholic temperament. The concept of ...
therapy-resistant depressionAn 8-week open trial was conducted to investigate whether patients with treatment-resistant, chronic depression and/or dysthymia could profit from high-dose thyroxine (T4) augmentation.Nine patients whose current depressive episode had lasted for a mean of 15.5 +/- 8.6 ...
Safety and tolerability of combined treatment with moclobemide and SSRIs: a systematic study of 50 patients Nineteen major depressed patients, resistant to previous pharmacotherapies, were treated by the addition of moclobemide (up to 600 mg/day) to paroxetine or... CJ Hawley,SJ Quick,S Ra...
Antidepressants resistant dysthymia cases have been studied. In those cases, it has been necessary to add lithium or thyroxine. This confirms that, when it comes to this disorder, there are many neurochemical mechanisms involved, given the positive response to the combination of drugs, ...
Specifically unipolar depression, treatment-refractory depression, resistant depression, anxious depression and dysthymia; 2-sulfamatomethyltetrahydropyrans and sulfamato-methylcyclohexanes, e.g. topiramatedoi:US20020094960 A1Anticonvulsant derivatives useful for treating depression as monotherapy or combination ...