However, no studies have analyzed the gut microbiota while focusing on susceptibility to KD. This study aimed to evaluate whether dysbiosis elevates susceptibility to KD by assessing children with a history of KD. Methods: Fecal DNA was extracted from 26 children with a h...
dysbiosisofthegutmicrobiotaindisease在疾病的肠道菌群失调 系统标签: microbiotadysbiosisgutdisease肠道失调 ENGIHRSUPPLEMENTDysbiosisofthegutmicrobiotaindiseaseSimonCarding1,2,KristinVerbeke3,DanielT.Vipond1,2,BernardM.Corfe4,5*andLaurenJ.Owen61InstituteofFoodResearch,Norwich,UK;2NorwichMedicalSchool,Universityof...
There is growing evidence that dysbiosis of the gut microbiota is associated with the pathogenesis of both intestinal and extra-intestinal disorders. Intestinal disorders include inflammatory bowel disease, irritable bowel syndrome (IBS), and coeliac disease, while extra-intestinal disorders include allergy...
gutMDisorder (http://bio-annotation.cn/gutMDisorder), a manually curated database, aims at providing a comprehensive resource of dysbiosis of the gut microbiota in disorders and interventions. Alterations in the composition of the gut microbial community play crucial roles in the development of chr...
Dysbiosis of the gut microbiome occurs when there is a disruption in the balance of the microbial community, leading to an overgrowth of harmful bacteria and a decrease in beneficial bacteria. This imbalance can lead to a wide range of health problems, including inflammation, immune dysfunction, ...
Chronic kidney disease (CKD) patients have an increased risk of cardiovascular diseases (CVDs). The present study aimed to investigate the gut microbiota and blood trimethylamine-N-oxide concentration (TMAO) in Chinese CKD patients and explore the underl
Ulcerative colitis (UC) is a chronic immune-mediated disorder, whose etiology is not fully understood and for which no effective treatment is available. Recently, research has focused on the dysbiosis of gut microbiome in UC. However, the results so far
Butyrate-producing bacteria (BPB) are potential probiotic candidates for inflammatory bowel diseases as they are often depleted in the diseased gut microbiota. However, here we found that augmentation of a human-derived butyrate-producing strain,Anaerostipes hadrusBPB5, significantly aggravated colitis in...
The incidence of sporadic young-onset colorectal cancer (yCRC) is increasing. A significant knowledge gap exists in the gut microbiota and its diagnostic value for yCRC patients. Through 16S rRNA gene sequencing, 728 samples are collected to identify mic
Correlation analysis defined microbe-metabolite clustering patterns unique to SBS-ALD and identified a metabolite panel that correlates with dysbiosis of the gut microbiome in SBS. Short bowel syndrome (SBS) occurs as a consequence of massive small bowel resection and is clinically character- ised by...