A molecular- level understanding of the origins of dysbiosis, its endogenous and environmental regulatory processes, and its downstream effects may enable us to develop microbiome-targeting therapies for a multitude of common immune-mediated diseases. This is a preview of subscription content, access ...
Levy M, Kolodziejczyk AA, Thaiss CA, Elinav E. Dysbiosis and the immune system. Nat Rev Immunol. (2017) 17:219-32. doi: 10.1038/nri.2017.7Levy M, Kolodziejczyk AA, Thaiss CA, et al. Dysbiosis and the immune system. Nat Rev Immunol 2017;17:219-32....
Immune-Microbiota Interactions: Dysbiosis as a Global Health Issue health and disease, the immune system and its interface with microbiota is a critical target in overcoming the health challenges of the twenty-first ... AC Logan,FN Jacka,SL Prescott - 《Current Allergy & Asthma Reports》 被引...
et al. The Arabidopsis gene CAD1 controls programmed cell death in the plant immune system and encodes a protein containing a MACPF domain. Plant Cell Physiol. 46, 902–912 (2005). CAS PubMed Google Scholar de Michele, R. et al. Free-flow electrophoresis of plasma membrane vesicles ...
Immune homeostasis is achieved and maintained due in part to the extensive interplay between the gut microbiota and host mucosal immune system. Imbalances of gut microbiota may lead to a number of pathologies such as obesity, type I and type II diabetes, inflammatory bowel disease (IBD), ...
Recently, microbial dysbiosis has been identified as one of the major factors involved in the onset and progression of AD. Imbalance in gut microbiota is known to affect central nervous system (CNS) functions through the gut-brain axis and involves inflammatory, immune, neuroendocrine and metabolic...
Microbiota modification through enhanced intestinal inflammation promotes α-synuclein folding disturbances, and the inflammatory response to α-synuclein [161]. Pathology of α-synuclein has the bidirectional associations with innate immune system and microbiome [162]. Bacterial endotoxin may alter α-...
Homeostasis and Inflammation in the Intestine The gut is home to our largest collection of microbes. The ability of the immune system to coevolve with the microbiota during postnatal life allows the ho... Wendy,S.,Garrett,... - 《Cell》 被引量: 1186发表: 2010年 Population Trends in the ...
INTRODUCTION All cells of the immune system that have been analyzed express the vitamin D receptor (VDR) including dendritic cells, macrophages, T cells, and B cells.1 The VDR is a nuclear receptor that is part of the steroid hormone superfamily of receptors that regulate gene transcription. ...
Bladder cancer is a common malignancy with high recurrence rate. Early diagnosis and recurrence surveillance are pivotal to patients’ outcomes, which require novel minimal-invasive diagnostic tools. The urinary microbiome is associated with bladder canc