metabolites, proteins, and RNA. They offer unique advantages in regulating microbial community homeostasis and treating diseases related to dysbiosis compared to traditional drugs. On the one hand
Research in this area is ongoing, but studies suggest that people with IBDs likeulcerative colitis have gut dysbiosisand that itdamages their intestines. Whether it’s the dysbiosis that causes IBD or that GI conditions such as IBD negatively impact the microbiome isn’t clear, says Dr. Friedma...
Semen has a unique microbiome; however, its origin and function need to be further investigated in order to understand its role in health and disease. Alterations in the bacterial composition of semen have been linked to a variety of disorders, including subinfertility and poor semen quality, pro...
Smoking affects the healthy oral, intestinal, and pulmonary microbiomes, often altering the dynamic equilibrium of the diverse bacteria that make up the human microbiome, or "dysbiosis". Smoking-induced dysbiosis can lead to developing conditions like asthma, chronic obstructive pulmonary...
The gut microbiome is closely associated with health status, and any microbiota dysbiosis could considerably impact the host’s health. In addition, many active consortium projects have generated many reference datasets available for large-scale retrospe
(siRNAs), piwi-interacting RNAs (piRNAs),circular RNAs(circRNA) andlong noncoding RNAs(lncRNAs). These non-coding RNAs have found a critical role in the maintenance of cellular and tissuehomeostasisand their dysregulation has been linked to the onset of various pathological conditions in affected ...
Collectively, imbalances or deviations in the gut microbiota (“dysbiosis”) can compromise intestinal barrier function (“leaky gut”) and vice versa, and both phenomena are tightly linked to multiple pathologies including inflammatory bowel disease (Fasano, 2020), celiac disease (Odenwald and Turner...
health. Dysbiosis, currently defined, involves perturbations to the structure of complex commensal microbial communities. It is a state of change that involves the loss of beneficial microorganisms, and/or the expansion of potentially harmful microbes, and/or the loss of overall microbial diversity [...
Our Review further evaluates soil microbial contributions to one health in the light of dysbiosis and global change and demonstrates that microbial diversity is generally positively associated with one health. Finally, we present future challenges in one health research and formulate recommendations for ...
Higher awarenessof stressors.Smoking, poor diet, age, environmental pollutants or factors, and diseased conditions can cause microbial dysbiosis; because these stressors upset the balanced state of microbiota. ———– P. S.Types of microbiota ...