Because the scientists have demonstrated a possible neurobiological function for this particular genetic variant, it is referred to as a "functional variation." "Knowing how this genetic variation could potentially modulate the effects of cocaine lends weight to our results," says Chen. "But, on th...
EFFECTS OF DYNORPHIN A (1-17) ON MOTOR FUNCTION AND SPINAL INTRACELLULAR MESSENGER SYSTEMS IN RAT 强啡肽A运动神经脊髓细胞内信号转导动物实验The effect of intrathecal injection of dynorphin A (1-17) on second messenger systems of spinal cord relative to behavioral change in rats was studied. ...
Dynorphin, the endogenous peptide for the kappa opioid receptor, is a complex neuropeptide known to exist in many forms, yet we do not have a good grasp of the function of each of these forms or fragments. Dynorphin was first purified, sequenced and named Dynorphin A (1–17) (Cox et al...
They appear to be involved in the perception of pain and the neural control of certain aspects of endocrine function, the regulation of movement, mood and some aspects of behaviour. When opium, morphine, heroin and related drugs are ingested they produce tolerance, withdrawal and addiction. ...
Regulation and function of spinal and peripheral neuronal B1 bradykinin receptors in inflammatory mechanical hyperalgesia. Pain 104, 683–691 (2003). Article CAS Google Scholar Burgess, S.E. et al. Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not ...
The peptide did not display a prejunctional modulatory action on the adrenergic nerves present in the vessels. The function of dyn B in the cerebrovascular nerves is discussed. 展开 关键词: SENSORY NERVE FIBER PARASYMPATHETIC NERVE TRIGEMINAL GANGLION CRANIAL PARASYMPATHETIC GANGLIA DYNORPHIN ...
aWould it still be possible to optimize the shuffle function?[translate] abetween abiotic and biotic compartments,and between trophic levels due to a combination of changing taxonomy and ecological function 在无活力和生物隔间之间和在食性层次由于改变的分类学的组合和生态学作用之间[translate] ...
CREB, a member of the basic leucine zipper family of the transcription factors, regulates a large and diverse group of gene transcription and function in cellular responses to various physiological stimuli, including neuro- transmitters, growth factors, and cell stress20. Specifically, the ...
Amphetamine-evoked c-fos mRNA expression in the caudate-putamen: the effects of DA and NMDA receptor antagonists vary as a function of neuronal phenotype a... Dopamine (DA) and glutamate neurotransmission is thought to be critical for psychostimulant drugs to induce immediate early genes (IEGs)...
Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin- releasing hormone receptor-2. Nat Genet 24: 403–409. Crawley JN (1999). Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, ...