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The art of the design principles of high‐performance adhesives lies in the regulation of adhesion and cohesion strengths. Compared with permanent covalent bonds, dynamic bonds, including dynamic covalent and noncovalent bonds, are vulnerable under mechanical stimuli but rebuildable, making them promising...
covalent bondsdynamic bondsnoncovalent bondsAdhesive materials have been widely used in almost every industrial domain. The art of the design principles of high鈥恜erformance adhesives lies in the regulation of adhesion and cohesion strengths. Compared with permanent covalent bonds, dynamic bonds, ...
S8, see Methods). Overall, our model suggests that efficient force transmission within the range of cellular retrograde flow speeds depends on the unfolding properties of Talin subdomains, their total number, as well as the strength of the integrin-Talin and Talin-actin bonds....
In this Review, we highlight an array of polymer materials designed with dynamic bonds and reconfigurable networks, and discuss the different classes of molecular-scale motifs used to realize dynamic behaviour. After surveying the fundamental polymer physics governing dynamic networks, we examine the ...
Additionally, the phenol-urethane crosslinked networks and rigid structures of the TA molecule enhanced the tensile strength and improved the biostability of the target elastomers. Cytotoxicity measurements were conducted to evaluate the biocompatibility of the PEU−TS elastomers. The innovative design ...
The strength and stability of neutrophil adhesion to an ICAM-1-expressing cellular substrate was imaged in a parallel plate flow chamber as a function of applied shear stress. By correlating the dynamics of adhesion with the expression and membrane distribution of mAb 327C reporting on activated ...
and lack of fatigue strength or endurance limit. Fatigue strength has been defined as the repeated loading and unloading of a specific stress on a material structure until it fails. Fatigue strength can be tensile or distraction, compression, shear, torsion, bending, or a combination of these. ...
The conversion of auditory and vestibular stimuli into electrical signals is initiated by force transmitted to a mechanotransduction channel through the tip link, a double stranded protein filament held together by two adhesion bonds in the middle. Altho
8. This shuttling contributes to the delivery of blood-borne antigens to follicular dendritic cells for display to follicular B cells. Retention of MZ B cells within the MZ depends on integrin-mediated adhesion, and blockade of integrin function leads to their loss into blood circulation8,9. ...