DNAtopologyknottingsupercoilingtopoisomeraseDNA topology changes dynamically during DNA replication. Supercoiling, precatenation, catenation and knotting interplay throughout the process that is finely regulated by DNA topoisomerases. In the present article, we provide an overview of theoretical and ...
Despite extensive studies on DNA replication, the exchange mechanisms of DNA polymerase during replication remain unclear. Existing models propose that this exchange is facilitated by protein partners like helicase. Here we present data, employing a combination of mechanical DNA manipulation and single flu...
DNA Replication | How, When & Why? from Chapter 4 / Lesson 2 78K Understand how DNA is replicated. Learn why DNA replicates, when DNA replicates, and how DNA replication works. Get an overview of the rates of replication of different cells. Related...
Yes, DNA supercoiling occurs during replication. In this light, the replication process changes the negatively supercoiled DNA into positively...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tough homework and...
ribonucleotides (rNTPs) are in excess over deoxyribonucleotides (dNTPs) in vivo, recent findings indicate that replicative DNA polymerases (DNA Pols) are able to insert ribonucleotides (rNMPs) during DNA synthesis, raising crucial questions about the fidelity of DNA replication in both Bacteria ...
Proliferative tissues, for example, hematopoietic stem cells, skin and intestine appeared less vulnerable, which can be explained by the ability of DNA replication to resolve DNA damage-stalled RNAPII, which shields lesions from repair by other mechanisms20. Moreover, cell division dilutes DNA ...
It is also involved in the replication and repair mechanisms of protein synthesis under ER stress conditions (Wang et al., 2003). The higher expression of HSP70A1A postpartum (especially at 3 and 35 d) in SU compared with SP cows together with microarray results indicates the activation of ...
Postreplication repair in E. coli: strand exchange reactions of gapped DNA by RecA protein. We have used a sensitive gel electrophoresis assay to detect the products of Escherichia coli RecA protein catalysed strand exchange reactions between gapped and duplex DNA molecules. We identify structures tha...
Replication stress causes replication fork stalling, resulting in an accumulation of single-stranded DNA (ssDNA). Replication protein A (RPA) and CTC1-STN1-TEN1 (CST) complex bind ssDNA and are found at stalled forks, where they regulate RAD51 recruitmen
Minichromosome maintenance 5 is involved in initiation of DNA replication in cell67. No reads were detected for fructose-bisphosphatealdolase 2 (AT4G38970; c43203_g3_i1), required for biomass accumulation68 in the developing ovules (0, 6, and 14 DAA) of small-seeded genotype. At hormone ...