The anti- dsDNA antibody was correlated with the occurrence of fever and arthritis(P<0.05); The anti-dsDNA could lead to AnuA, increase the positive rate of anti-U1RNP antibody and content of IgG,and cut down C3 level (P<0.05). Conclusion The clinical manifestation and changes of ...
Results Among pts who were anti-dsDNA-positive at BL, significant decreases of anti-dsDNA antibodies were observed for BARI 2-mg and 4-mg compared to PBO beginning at Wks 2 and 4, and continuing through Wk 24. Reductions of IgG levels were found for BARI-treated pts, including significant...
【摘要】目的比较狼疮肾炎(LN)患者和非LN的系统性红斑狼疮(SLE)患者血清IgG抗dsD— NA抗体及其亚型的分布,探讨抗dsDNA抗体与LN病理间的关系,为IN的早期诊断和制定治疗 方案提供依据.方法以健康个体为正常对照组,病例组选自两所三甲医院住院的SLE患者,病 例组又分为LN和非LN两组,采用双抗夹心酶联免疫吸附试验测定...
The anti-dsDNA antibody was correlated with the occurrence of fever and arthritis(P<0.05); The anti-dsDNA could lead to AnuA, increase the positive rate of anti-U1RNP antibody and content of IgG,and cut down C3 level (P<0.05). Conclusion The clinical manifestation and changes of ...
ROC ' curve to analyze the A U C ' value,and to explore the diagnoslic value of several diagnostic indicators；and using artificial m e t h o d s lo calculate the sensitivity .specificity, positive predictive value and negative predictive value of each index through calculation formula....
建议收到Double Stranded DNA (dsDNA) Antibody (IgG), BioAssay ELISA Kit (Human)产品后将其置于4°C/-20°C保存。 其他 Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50...
肾功能指标如尿素、肌酐及尿酸，电解质如钾、氯及钙离子等水平显著高于未合并肾损伤组，免疫球蛋白IgG、IgA 及补体C3等水平显著低于未合并肾损伤组，差异有统计学意义（P < 0.05）。结论 抗dsDNA、抗核小体、抗组蛋白等自身抗体、补体C3及多项实验室指标可能与SLE 患者肾损伤相关。[ 关键词 ] 系统性红斑...
[doc] IgG型抗dsDNA抗体及其亚型与狼疮肾炎临床和病理关系探讨 热度: 五种方法检测抗dsDNA抗体性能比较与临床评价 热度: 分类号:密级: 学号:2010109087单位代码:10759 石河子大学 硕士学位论文 AnuA、抗dsDNA抗体和抗dsDNA-NcX抗体与SLE 的相关性研究 学位申请人刘艳慧 ...
AB0199Could anti-ribosomal P protein IGG autoantibodies be important for systemic lupus erythematosus diagnosis? BackgroundSystemic lupus erythematosus (SLE) is characterized by multi-organ involvement and the production of autoantibodies directed against several nuclear proteins, among which the most ...
The antibody isotype can be IgG (IgG1, IgG2, IgG3, IgG4), IgM, IgA, IgE, or IgD. In some embodiments, the chimeric antibody comprises complementarity determining regions (CDRs) derived from a non-human animal. In some embodiments, chimeric antibody comprises a variable region derived from...