ds-HMGB1 directly activated the kynurenine pathway and cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) in the hippocampal tissue. Conversely, fr-HMGB1 upregulated the aforementioned factors only following treatment with H2O2. These findings indicated that ds-HMGB1...
恒州博智(QYResearch)调研团队最新发布的【2024年全球HMGB1抗体行业总体规模、主要企业国内外市场占有率及排名】,本文侧重研究全球HMGB1抗体总体规模及主要厂商占有率和排名,主要统计指标包括HMGB1抗体产能、销量、销售收入、价格、市场份额及排名等,企业数据主要侧重近三年行业内主要厂商的市场销售情况。地区层面,主要分析过...
肠黏膜claudin-1蛋白表达降低,肠组织HMGB1mRNA表达升高,claudin-1 mRNA的表达降低.与模型组比较,EP处理组肠组织HMGB1 mRNA表达降低,claudin-1蛋白与mRNA表达升高,各损伤指标均明显改善.结论:SAP肠黏膜屏障损伤可能与肠组织HMGB1表达升高,从而下调紧密连接蛋白claudin-1的表达有关;HMGB1抑制剂EP对SAP肠黏膜屏障损伤具有...
DsRed-mediatedoligomerizationChromatin\\{FRAP\\}High-mobility group box-1 (HMGB1) is remarkably mobile in living cells, which reflects its ability to interact only transiently with both \\{DNA\\} and protein. This property is likely essential for \\{HMGB1\\} nuclear activities. Nonetheless the...