Describe the mechanisms of action associated with drugs that inhibit cell wall biosynthesis, protein synthesis, membrane function, nucleic acid synthesis, and metabolic pathways An important quality for an antimicrobial drug isselective toxicity, meaning that it selectively kills or inhibits the growth of...
Drugs that can NOT inhibit bacterial cell wall includeA.PGB.Semisynthetic penicillinsC.CephalosporinsD.GlycopeptidesE.β-lactamase inhibitor的答案是什么.用刷刷题APP,拍照搜索答疑.刷刷题(shuashuati.com)是专业的大学职业搜题找答案,刷题练习的工具.一键将文档转
intefere with protein synthesis or function What is the drawback to using drugs that disrupt proteins? Although bacterial and human ribosomes are different, human mitochondria have a bacterium like ribosome and can be impacted Ways to disrupt proteins Inhibit protein synthesis initiation, interfere wit...
Echinocandins are a new class of antifungal drugs[1] that inhibit the synthesis of glucan in the cell wall, via noncompetitive inhibition of the enzyme 1,3-β glucan synthase[2][3] and are thus called “penicillin of antifungals”[4] (a property shared with papulacandins) as penicillin ha...
Caspofungin (Cancidas®) is the first of a new class of antifungal agents, the echinocandins, that inhibit the synthesis of the fungal cell wall component β-(l,3)-D-glucan. Caspofungin is administered once daily by slow intravenous infusion and is used to treat infections caused byCandidasp...
(2) act directly on the cell membrane of the microorganism and affect its permeability, and leading to leakage of intracellular compounds; (3) inhibit protein synthesis; (4) affect bacterial nucleic acid metabolism; (5) The antimetabolites of folic acid, that can block essential enzymes of ...
Carbapenems are a beta-lactam antibiotic class with a broad spectrum of activity that are structurally related to the penicillins. Examples include: meropenem, ertapenem, and imipenem-cilastatin (Primaxin). Carbapenems are noted for their ability to inhibit extended spectrum beta-lactamase enzymes and...
Oritavancin diphosphate is a glycopeptide analog related to the vancomycin class of antibiotics that inhibits the transpeptidase and transglycosylation steps of bacterial peptidoglycan cell-wall synthesis.197, 198 The compound was discovered and initially developed by Eli Lilly and Co. The development of ...
SQ109 (21) was found among synthetic ethambutol analogs and is considered to be a next-generation drug that replaces ethambutol.93 Its mechanism of action is thought to be the inhibition of cell wall synthesis, and it shows a bactericidal effect against ethambutol- susceptible and ethambutol-...
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an increase in interest in alternate therapies. Peptide-based drugs