Cells were treated for 24 h with either DMSO control, 1.3 μM salinomycin or 0.2 μM of avermectin, ivermectin, conglobatin A, ophiobolin A, kazusamycin B, leptomycin B or streptonigrin. Inhibitors are color-coded by chemical class as in Supplementary Table 4. Red dotted line denotes the...
aphidicolin,a diterpene-type antibiotic produced byCephalosporium aphidicolaPetch, inhibited the growth of either HSV-1 or HSV-2, in vitro and in vivo (Bucknall et al.1973). In vitro results demonstrated that aphidicolin, administered on infected human embryonic lung cells, inhibited the growth of ...
Outside of human cells, peptides that replicate ACE2 could be effective for containing COVID, and they offer a few advantages over tiny molecules (higher confidence) and antibodies (lower cost) (little size). Arrangements in the beneficial gaps in the COVID S-circle yielded intense inhibitors ...
Dau daunomycindaunomycinDDS drug delivery systemsdrug delivery systemsUse of macromolecular water-soluble carriers of anti-cancer drugs represents a promising approach to cancer therapy. Release of drugs from the carrier system is a prerequisite for therapeutic activity of most macromolecular anti-cancer...
Tylocin, Carbomycin A, Sparsomycin, Lincomycin, Cethromycin, Telithromycin, and Quinupristin; together with one or more selected from a group consisting of the 50S subunit inhibiting antibiotics which bind near the PTC Clindamycin, Dalfopristin, Chloramphenicol, Linezolid, Tiamulin, and Lincomycin. ...
中国一类新药汇总(SummaryofnewdrugsinChina) SummaryofanewdruginChina Assumes Xiaohezi7844(goldcoin+0,VIP+0):Thanks Xiaohezi7844(goldcoin+3,VIP+0):Thanks Lwf991229(goldcoin+1,VIP+0):3Q~thankyouforsharing~! ThispaperintroducessomenewdrugsdevelopedinChina,and ...