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Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. Nat Commun. 2018;9:1825. Article PubMed PubMed Central Google Scholar Gamazon ER, Wheeler HE, Shah KP, Mozaffari SV, Aquino-Michaels K, Carroll RJ, et al. A gene-based ...
Structure-based drug design attempts to use the structure of proteins as a basis for designing new ligands by applying accepted principles of molecular recognition. The basic assumption underlying structure-based drug design is that a good ligand molecule should bind tightly to its target. Thus, one...
Institute for Medical Informatics, Statistics & Documentation, Medical University of Graz, Graz, Austria Andreas Holzinger Corresponding author Correspondence to Pinar Yildirim. Additional information Competing interests The authors declare that they have no competing interests. Authors' contributions Authors con...
Work addiction refers to the problem of compulsive overworking, conceptualized as an addictive disorder. It has substantial epidemiological significance due to high prevalence rates (ranging from about 7% to 20% depending on the country); harm to self an
Centers for Medicare & Medicaid Services https://www.cms.gov/Research-Statistics-Data-and-Systems/Statistics-Trends-and-Reports/NationalHealthExpendData/NHE-Fact-Sheet (2021). Congressional Budget Office. Offsetting effects of prescription drug use on Medicare’s spending for medical services. ...
For ophthalmic use:erythromycin base (ointment) Adverse effectsGastrointestinal disturbances, such as diarrhea, nausea, abdominal pain, and vomiting, are very common because erythromycin is a motilin agonist.[17] Because of this, erythromycin tends not to be prescribed as a first-line drug....
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Globally recognized genetic modification with time has supported the emergence of versatile and novel featured organisms in nature, some of which can be analogized with Pandora’s box elements; likeMycobacteriumsp. which has revived itself again after again in a repetitive order over decades and, gr...