In contrast, diphenhydramine and sodium bicarbonate were ineffective as local antidotes. Topical skin cooling, however, significantly increased vinca-induced skin ulcers for VBL, VDS, and VCR (P less than .05). Hydrocortisone, vitamin A topical cream, and isoproterenol increased skin toxicity. [3H]...
Drugs and Antidotes in Acute Intoxication GeorgeBraitberg, inCritical Care Nephrology (Third Edition), 2019 Abstract Drug intoxication and overdose are growing problems. A significant proportion of patients overdose intentionally, whereas many others become intoxicated as a result of therapeutic misadventure...
Critical insights into timely topics such as biological warfare agents and the newest antidotes Updated information on industrial chemicals, including the most recent regulatory exposure limits Expanded information, including special pregnancy considerations Easy-to-read text and tables containing specific drug...
This may consist of hyperthermia, hypertension, electrolyte imbalances, seizures, intra-cerebral bleed, respiratory depression, cardiac arrest, acute renal injury, agitation, panic attacks, acute psychosis, delirium and coma. Management of cases of toxicity is mostly supportive as antidotes are available...
The addition of a strong inhibitor or inducer of these enzymes multiplies the toxicity or deletes the effective action of many drugs. It is also important to know the effects of these inhibitors or inducers on substrates other than theophylline and terfenadine. Some substrates are naturally ...
Carbamazepine poisoning, usually accidental and sometimes secondary to the coadministration of other drugs, yields a clinical picture with neurological and cardiovascular signs. The outcome is usually favourable, sometimes with spontaneous improvement, and death is a distinct rarity. No specific antidotes ...
Comprehensive treatment requires a knowledge of general life support, and the specific treatment of various overdoses which includes knowledge of how to remove the poison, how to inactivate the poison, and finally what specific antidotes are available. For in depth reading on this topic, the ...
Monitoring stage errors include inadequate laboratory monitoring of drug therapies or a delayed response or failure to respond to signs or symptoms or laboratory evidence of drug toxicity. For a single adverse drug event, it was possible to identify errors at more than 1 stage of pharmaceutical ...
Supportive care alone may be sufficient treatment without administration of antidotes for many cases of cyanide intoxication, particularly in conscious patients without signs of severe toxicity. Patients should be closely monitored to ensure adequate perfusion and oxygenation during treatment with Amydramine...
POISONINGDRUGdeliverysystemsBIOTERRORISMMONOCLONALantibodiesTREATMENTThe high toxicity of ricin and its ease of production have made it a major bioterrorism threat... Respaud,Renaud,Marchand,... - 《Journal of Controlled Release》 被引量: 7发表: 2016年 Taylor & Francis Online :: Residues of the be...