Poust, Chemical kinetics and drug stability, in: G.S. Banker, C.T. Rhodes (Eds.), Modern Pharmaceutics, 4th ed., Marcel Dekker, New York, USA, 2002, pp. 158-159.Guillory JK. Poust RI, eds. Chemical kinetics and drug-stability. 4th ed. New York: Marcel Dekker; 2002. P. 139- ...
ChemInform Abstract: Chemical Kinetics and Drug Stability Review: 138 refs. D Attwood,RI Poust - 《Cheminform》 被引量: 19发表: 2011年 Kinetics and Mechanism for the Reaction of Cysteine with Hydrogen Peroxide in Amorphous Polyvinylpyrrolidone Lyophiles amorphous solidschemical kineticscysteinedrug ...
This needs to be optimised with due consideration to other factors which may influence the measurement over time, such as the stability of the recombinant protein or membrane preparation, cell viability, or regulation of the ligand occupied receptors in whole cells over time. In some instances, a...
In addition, as RNA editing and posttranscriptional modifications are critical for RNA stability and biological function, very recent studies have also demonstrated the alteration of DMPK gene expression following RNA editing145, 146, 147. Future studies in these areas will undoubtedly advance our ...
Therefore, we applied the L-RIP55 perturbation MD approach to investigate the stability of the α-helix3 interaction network. Perturbation of residues located in the lid-part of α-helix3 (residues 110-116) initiate the most pronounced conformational changes (Supplementary Fig. 13a), which ...
A non-active substance formulated with an active pharmaceutical ingredient to enhance physicochemical characteristics such as stability and solubility. Opsonization The process by which foreign materials are coated with opsonin proteins to enhance their phagocytic uptake and clearance. Semi-telechelic A poly...
Studies of peptide drug stabilization strategies thus provide a useful point of departure for considering the stability of glycopeptides. In this review, we discuss the factors that affect the chemical and physical integrity of glycopeptides in aqueous solution. The main difference between peptides and...
Drug Stability:药物稳定性.ppt,Drug Stability Outline Introduction – The Importance of Drug Stability Regulatory Aspects Degradation Pathways and Mechanisms Experimental Methods Kinetics Physical Stability Diamonds are Forever Drugs Have A Shelf Life Th
In-depth investigation of the structure-function relationship of drug delivery systems based on cell-penetrating peptides, lipid nanoparticles and polymeric colloidal, and biophysical and biochemical stability of peptide, protein, monoclonal antibody, and vaccine, as the integrative efforts on drug product...
pores and Charged NPs when adsorbed on liposomal surface, reduces surface tension as well as create steric repulsion that prevents fusion ofliposomesultimately leading to their stability.139–141Using this strategy, pH-sensitive drug release can be achieved by employing ionic liposomes coupled with ...