Paul, D.; Cowan, K.H. Drug resistance in breast cancer. In Breast Cancer Molecular Genetics, Pathogenesis, and Therapeutics. To- towa (NJ): Humana Pres; 481-517.Paul D, Cowan KH. Drug resistance in breast cancer. In: Breast Cancer Molecular Genetics, Pathogenesis and Therapeutics. Bowcock...
Drug Resistance in Breast Cancerdoi:10.1385/0-89603-560-3:481PaulCowan
Definition Breast cancer drug resistance refers to the failure of chemotherapy at the outset of treatment or at some point after treatment has commenced. Resistance can thus be defined as intrinsic or acquired, depending upon presentation. Intrinsic Drug Resistance Drug resistance that is present from...
Drug resistance in breast cancer 来自 钛学术 喜欢 0 阅读量: 35 作者: H Lage 摘要: Resistance to cytotoxic chemotherapy is the main cause of therapeutic failure and death in women suffering on breast carcinoma. Commonly, patients refractory to chemotherapeutic treatment regimens show resistance to ...
(TME) is vital in modulating the immunotherapy response. Various tumor microenvironmental components, such as cancer-associated fibroblasts (CAFs), tumor-associated macrophages (TAMs), and myeloid-derived suppressor cells (MDSCs), are involved in TME modulation to cause immunotherapy resistance. This ...
Striking Back at Drug Resistance Using a combination of genomic, cellular, biochemical and structural approaches, the researchers found that the way these cytokines alter the estrogen receptor are sufficient to induce growth ofbreast cancer cellsin the absence of estrogen, precisely what happens when ...
Breast cancer (BC), as a heterogeneous disease, is considered as one of the most common malignancies in women worldwide. The resistance of BC cells to therapeutic agents has remained a big challenge in the treatment of BC patients. Some factors such as cytokines, exosomes, and soluble ...
Research recently published in Drug Resistance Updates has revealed a previously unknown biological process through which breast tumor cells develop resistance to standard treatment, which could open the door for cancer scientists around the world to fur
Taken together, our data suggest a potential role of hPXR in breast cancer resistance to drug treatments.doi:10.4161/cbt.8.13.8696Chen, YakunTang, YongChen, ShuqingNie, DaotaiTaylor & FrancisCancer Biology & Therapy
Breast cancer (BC) is a significant cause of cancer-related deaths among women worldwide. Hypoxia, a common feature of solid tumor, is associated with drug resistance and a poor prognosis in BC. In this study, we present a strategy to overcome hypoxia-induced chemotherapy tolerance in BC. Sp...