The reported values for precision, recall, and F-measure of each method is based on the best value of the threshold for the output. It should be noted that if the interaction of two drugs is assigned to zero, it denotes that no evidence of their interaction has been found yet; thus, ...
DREEP’s performance is estimated using either precision-recall curve (upper) or ROC curve (bottom). Max AUC of ROC curves are CTRP2 = 0.691, GDSC = 0.728, and PRISM = 0.661. D Left column: Each point is a drug whose y-coordinate is AUC of the corresponding ROC curve ...
The recall applies to more than 302,000 bottles of the drink. Feb 17, 2023 FDA joins investigation into contaminated cough syrups that killed 300 kids None of the contaminated products have been sold in the United States, the agency told CBS News. Jan 26, 2023 FDA looking to simpli...
In December 2023, the European Medicines Agency published a list of more than 200 critical medicines to avoid potential shortages – it deems a medicine critical according to two main criteria: the seriousness of the disease it targets and the availability of alternative medicines. The ...
(Compound, Disease target) pairs. Here, the hypotheses shown in Fig.4suggest that the possible paths from Fosinopril to nsp13 in the KG include more than one step. This apparently contradicts the direct binding hypothesis evaluated above by molecular docking. However one should recall here that...
Standardized List of Renally Eliminated Drugs Health care professionals are expected to recall a compendium of drugs that require renal dosage adjustments. This expectation can be even more complex when various drug information sources provide conflicting data.28 It is this lack of drug knowledge that...
(molecular fingerprint ECFP4, and pre-trained representation KPGT). We conducted a hyperparameter search for n_estimators, max_depth, criterion and obb_score to find the optimal model. To evaluate the model performance, we mainly used the area under the Precision–Recall curve (AUPR), and ...
Risk control drives risk assessment and risk review: A cause and effect model of pharmaceutical drug recall on patient safetydoi:10.1177/27550834231170075PATIENT safetyPHARMACEUTICAL industryFUZZY decision makingOUTPATIENT medical careRISK communication
Let’s take a look at the four drugs on the WADA Prohibited List that are of Russian or Eastern European origin and explore alternatives that athletes may be using today. The story starts with bromantan, which was developed in the 1980s at the Russian Academy of Medical Sciences in Moscow...
Zofran Recall In December 2012, the FDA notified health care professionals that the 32 mg, single intravenous dose of Zofran would no longer be marketed because of the potential for serious cardiac risks. The FDA said in its Drug Safety Communication that it was working with the manufacturers of...