Introduction Drug induced lupus erythematosus to various anti epileptic drugs is a known entity in adults with fewer cases reported in children. The presentation is vague and needs a high index of suspicion to diagnose this condition which has a potential to cause significant morbidity. It should ...
Drug-induced lupus erythematosus (DI-LE) is defined as an entity characterized by clinical manifestations and immunopathological serum findings similar to those of idiopathic lupus but which is temporally related to drug exposure and resolves after withdrawal of the implicated drug. Similarly to idiopath...
Totoritis MC, Rubin RL. Drug-induced lupus. Genetic, clinical and laboratory features. Postgraduate Medicine 78: 149–161, 1985 Totoritis MC, Tan EM, McNally EM, Rubin RL. Association of antibody to histone complex H2A-H2B with symptomatic procainamide-induced lupus. New England Journal of Med...
Two cases of late-onset drug-induced lupus erythematosus caused by ticlopidine in elderly men We have experienced two cases of drug-induced lupus erythematosus caused by ticlopidine in the last three years. Both were late-onset cases (1 and 4 ......
lupus, and standardized criteria for the diagnosis of drug-induced lupus have not been established. The mechanism(s) responsible for the development of drug-induced lupus may vary depending on the drug or even on the patient. Besides lupus, other autoimmune diseases have been associated with ...
Lupus Anticoagulants and Antibodies to Phospholipids-Reply Although there is apparent agreement regarding an absence of thrombosis with antiphospholipid antibody complicating infectious disease, we found that drug-induced antiphospholipid antibodies were associated with thrombosis. Our findings are in ... Brandt...
The early diagnosis of drug-induced TMA may be vital. Strict monitoring of renal function, urine and blood abnormalities, and arterial pressure has to be performed in patients undergoing therapy with potentially toxic drugs. The drug must be discontinued immediately in the case of suspected TMA. ...
摘要: The AA. in this note II report the most recent acquisitions about the clinical features, hematology and serology of Systemic Lupus Erythematosus. Moreover describe the main characteristics of Discoid Lupus Erythematosus and of Lupus due to drugs....
Polymer–drug conjugates have long been a mainstay of the drug delivery field, with several conjugates successfully translated into clinical practice. The conjugation of therapeutic agents to polymeric carriers, such as polyethylene glycol, offers severa
A biological drug conjugates for binding human lupus anti-dsDNA autoantibodies; antibody inhibitor; conjugated with carbohydrates, drugs, lipids, lipopolysaccharides, peptides, proteins, glycoproteins, single-stranded or double-stranded oligonucleotides, hapte...